Test Offers Truth About Prion Disease
The U.S. FDA approved a new blood test that detects tau and amyloid plaques in the brain, a key indicator of prion disease, including Alzheimer’s disease, Parkinson’s disease, and Creutzfeldt-Jakob disease. The test detects these deadly proteins in blood, which is not good news.
The test is cleared for use in adults aged 55 and older who exhibit signs and symptoms of Alzheimer’s disease (and should detect other forms of prion disease). The Lumipulse Plasma Ratio test, developed by Fujirebio Diagnostics, offers a less invasive and more accessible alternative to traditional diagnostic methods.
The test measures the levels of two proteins, pTau217 and β-amyloid 1-42, in human plasma. It then calculates their ratio, to determine the presence or absence of amyloid plaques in the brain. Clinical trials have shown that the Lumipulse test demonstrates 91.7 percent accuracy in identifying amyloid plaques in positive cases and 97.3 percent accuracy when confirming their absence in negative cases.
Two FDA-approved drugs, Leqembi and Kisunla, have shown promise in slowing the progression of Alzheimer’s disease by targeting and removing amyloid plaques. However, their use requires confirmation of plaque presence, which underscores the importance of the new blood test.
Both the blood test and the treatments are primarily relevant for individuals with early-stage Alzheimer’s disease and those who exhibit symptoms.
The blood test helps confirm the presence of amyloid plaques, which is important for determining eligibility for treatment.
Biogen is betting big on Leqembi, but it must overcome concerns about cost, efficacy and side effects. Biogen has partnered with Fujirebio, while rival Eisai is collaborating with C2N, to clinically advance and commercialize blood tests that can detect Alzheimer’s disease.
The test can’t distinguish which region of the brain is under attack. After a positive test, neurologists must observe symptoms, including movement and memory, to distinguish between Alzheimer’s disease, Parkinson’s disease, and Creutzfeldt-Jakob disease. Currently, most insurance companies, including Medicare, Medicaid, and private insurance, do not cover the cost of the test.
Clearly, the blood test is a big step in the right direction. Millions of people are going undiagnosed and untreated. Unfortunately, neurodegenerative disease will continue to escalate around the world. Answers begin with the truth.
The bad news is that Alzheimer’s disease, Parkinson’s disease, and Creutzfeldt-Jakob disease are all forms of prion disease, which is a much more accurate and inclusive word when discussing neurodegenerative disease. Prion disease strikes most, if not all mammals, including cattle, deer, elk, moose, reindeer, camels, elephants, whales and many more. The outbreak has been in motion for years. So has the cover up.
A prion (pree-on) is a deadly form of protein that infects the entire body, while consuming the brain. Prion disease is clinically known as transmissible spongiform encephalopathy (TSE). As mentioned above, TSEs are transmissible. Most hospitals, neurologists, surgeons, coroners and even morticians are aware of the prion threat. Unfortunately, family members and caregivers are not being warned.
As mentioned earlier, the new blood test detects tau and beta amyloid in blood. Unfortunately, tau and beta amyloid also are known as prions.
Dr. Stanley Prusiner won the Nobel Prize in 1997 for his pioneering work on prions. In June 2012, Prusiner confirmed that Alzheimer’s disease, Parkinson’s disease, Huntington’s and even ALS are prion diseases. Unfortunately, much of his science is being ignored by policymakers and industry. Corruption and collusion among government and industry has put the entire planet at risk to the prion pathogen.
The bad news is that people and other mammals with prion disease are infectious. People are infecting animals and animals are infecting people. People are infecting people. As populations of people and animals get sicker, waste streams become deadlier. We all are caught in the crossfire.
“Good news is rare in the world of prions,” said Gary Chandler, CEO of Crossbow Communications. “This new blood test is no exception. This so-called breakthrough is just further confirmation that prions are in blood, bodily fluids and cell tissue of victims. Deadly prions migrate, mutate, multiply and kill. People with prion disease are a serious threat to public health.”
In other words, people with prion disease are walking time bombs. They are contaminating the world around them in ways that can’t be sterilized or stopped. The misinformation and mismanagement of prions is criminal. Thanks to lies by the US EPA and others, prions are being injected into our food and water supplies. Thanks to lies by other policymakers, the blood supply and blood products are hopelessly contaminated. Medical and dental facilities are exposing patients to deadly prions daily.
People with prion disease are donating blood and organs to innocent and unsuspecting victims. Municipalities and farmers are dumping tons of human sewage sludge (infectious waste) on farms and ranches, where it proceeds to permanently infect our food and water supplies. Golf courses, parks, forests and beyond are part of this illegal dumping program (missing risk assessments). The blood test is an alarm bell that could have and should have been sounded years ago.
Prion disease is now the fastest-growing cause of death in the world. The truth is more elusive than a cure. Many factors are contributing to the surge, including misinformation, disinformation and reckless public policies.
The medical term for ALS, Alzheimer’s disease, Parkinson’s disease, Creutzfeldt-Jakob disease, mad cow disease, chronic wasting disease and related diseases is transmissible spongiform encephalopathy (prion disease). The operative word is “transmissible.”
Despite the smoke and mirrors, the major difference between all of these forms of neurodegenerative disease is the species under attack by infectious prions. The primary difference between Alzheimer’s disease and Parkinson’s disease, for example, is the region of the brain that is under attack by the pathological protein.
Livestock, wildlife and humans have been exchanging prion disease for years. It’s a vicious circle that can’t be stopped. The truth is our only hope. The new blood test offers hope in the form of truth. Answers begin with the truth.
There are proven strategies to help avert neurodegenerative disease, including nutrition, exercise and prion aversion. There is not a cure for prion disease, but smart nutrition can ease the symptoms.
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