Is Alzheimer’s Disease Contagious

Science, Evidence Proving Transmissibility

If you think that you and your family are immune to the surging epidemic of neurodegenerative disease, think again. Neurodegenerative disease, including Alzheimer’s disease, is the fastest-growing cause of death in the world. It’s getting worse every day thanks to mismanagement and misinformation.

Infectious proteins known as prions are involved with most forms of neurodegenerative disease. Prion disease is known in neurology as transmissible spongiform encephalopathy (TSE). The operative word is “transmissible.” The global epidemic has more to do with the prion contagion than age.

Dr. Stanley Prusiner, an American neuroscientist from the University of California at San Francisco, earned a Nobel Prize in 1997 for discovering and characterizing deadly prions and prion disease. Prusiner claims that all TSEs, including Alzheimer’s disease, are caused by prions.

Prions and Alzheimer's disease

President Obama awarded Prusiner the National Medal of Science in 2010 to recognize the importance of his research. According to Prusiner, TSEs are a spectrum disease. Creutzfeldt-Jakob disease, which is extremely aggressive and extremely transmissible, is at the extreme end of the spectrum. Unfortunately, Prusiner’s science is being ignored and we are facing a public health disaster because of the negligence.

Neurologists are just guessing when they make a diagnosis on the prion spectrum. If the patient exhibits memory problems, they are labeled with Alzheimer’s disease. If they have a movement disorder, they are diagnosed with Parkinson’s disease. If the person exhibits extreme symptoms of both, they are diagnosed with Creutzfeldt-Jakob disease (CJD). It’s far from a science. Neurologists don’t know where along the spectrum the disease becomes transmissible. The entire spectrum could represent a transmissible disease. Unfortunately, neurologists are not warning these patients and their caregivers about the risks of exposure. Even those with Creutzfeldt-Jakob disease are not quarantined. They are sent home, where they can infect friends, family, caregivers, clinics, dental offices, restaurants and entire communities.

“There has been a resurgence of this sort of thinking, because there is now real evidence of the potential transmissibility of Alzheimer’s,” says Thomas Wiesniewski M.D. a prion and Alzheimer’s researcher at New York University School of Medicine. “In fact, this ability to transmit an abnormal conformation is probably a universal property of amyloid-forming proteins (prions).”

A study published in the journal Nature renews concern about the transmissibility of Alzheimer’s disease between people. A second study released in early 2016 by the same scientist adds to the stack of evidence.

According to neuroscientist Laura Manuelidis, at least 25 percent of Alzheimer’s diagnoses are wrong. These misdiagnoses are actually CJD, which is further up the prion spectrum. CJD, without dispute, is extremely infectious to caregivers and loved ones.

Alzheimer's disease and caregivers

Studies confirm that people and animals dying of prion disease contaminate the environment around them with prions because prions are in the skin, urine, feces, blood, mucus and saliva of each victim. Each victim becomes an incubator and a distributor of the Pandora-like pathogen. Victims are contagious long before they exhibit clinical symptoms.

At the personal level, this is very bad news for caregivers, especially spouses, who are 600 percent more likely to contract neurodegenerative disease from patients (Duke University and Utah State University). A cough, sneeze, utensils and drinking glasses all become lethal pathways. Once an item is contaminated, it’s impossible to sterilize. The human prion is resistant to both heat and chemicals. It’s reported that prions released from people are up to a hundred thousand times more difficult to deactivate than prions from most animals. Prions are not alive, so they can’t be killed.

Wastewater treatment plants are collecting points for prions from infected humans. The sewage treatment process can’t stop prions from migrating, mutating and multiplying before being discharged into the environment where they can kill again. The bad news is that the prions are being released back into the environment and dumped openly on land. The wastewater is being reclaimed and used for irrigating crops, parks, golf courses. It’s even being recycled as drinking water.

wastewater treatment plant

Claudio Soto, PhD, professor of neurology at the University of Texas Medical School in Houston, and his colleagues confirmed the presence of prions in urine. Soto also confirmed that plants uptake prions and are infectious and deadly to those who consume the infected plants. Therefore, humans, wildlife and livestock are vulnerable to prion disease via plants grown on land treated with sewage sludge and reclaimed sewage water.

Prion researcher Dr. Joel Pedersen, from the University of Wisconsin, found that prions become 680 times more infectious in certain soils. Pedersen also found that sewage treatment does not inactivate prions. Therefore, prions are lethal, mutating, migrating and multiplying everywhere sewage is dumped.

“Our results suggest that if prions enter municipal wastewater treatment systems, most of the agent would bond to sewage sludge, survive anaerobic digestion, and be present in treated biosolids,” Pedersen said.

joel pedersen prion research

“Land application of biosolids containing prions represents a route for their unintentional introduction into the environment. Our results emphasize the importance of keeping prions out of municipal wastewater treatment systems. Prions could end up in sewage treatment plants via slaughterhouses, hospitals, dental offices and mortuaries just to name a few of the pathways. The disposal of sludge represents the greatest risk of spreading prion contamination in the environment. Plus, we know that sewage sludge pathogens, pharmaceutical residue and chemical pollutants are taken up by plants and vegetables.”

Thanks to more and more people dying from TSEs, wastewater treatment systems are more contaminated with prions than ever. Wastewater treatment plants are now prion incubators and distributors. The prion problem is getting worse every day.

biosolids land application sewage sludge

The U.S. Environmental Protection Agency (EPA) has confirmed that prions are in sewage and that there has been no way to detect them or stop them. As such, the EPA has never issued guidance on prion management within wastewater treatment plants. Unfortunately, the EPA’s risk assessment on sewage sludge and biosolids were prepared before the world of science knew about prions. The agency continues to cling to its antiquated sludge rule crafted back in the dark ages. It does, however, consider prions a “contaminant of emerging concern.” Meanwhile, its outdated risk assessments are promoting a public health disaster.

“Since it’s unlikely that the sewage treatment process can effectively deactivate prions, adopting measures to prevent the entry of prions into the sewer system is advisable,” said the Toronto Department of Health, November 2004.

Exposing crops and livestock to prions is a very bad idea. Plants absorb prions from the soil along with water and nutrient uptake, which makes the prions even more bioavailable and infectious to humans, wildlife and livestock.

chronic wasting disease

Unfortunately, the damage is real. Deer, elk, moose and reindeer are contracting an unstoppable prion disease now. In deer, the government calls prion disease chronic wasting disease. In cattle, prion disease is called bovine spongiform encephalopathy (they might as well call it what it is—transmissible spongiform encephalopathy). Mad cow disease is the term that most of us know. The government pretends that there is a specific prion responsible for each of these diseases. The fact is that there are thousands of mutations of prions spreading in the environment and food chain now. Some kill quickly, while some are less lethal. The only thing that we need to know is that a deadly prion is a deadly prion. There is no species barrier.

mad cow disease

If prion disease is killing these animals, livestock are not immune. Beef and dairy cattle are consuming these infected crops and the infected water supplies, too. Since humans are at the top of the food chain, and since we are often downstream from these infected farms, ranches and forests, our food and water supplies are being compromised. Wind and tornadoes transport the infectious waste even further.

So, is Alzheimer’s disease transmissible? There is absolutely no evidence to the contrary. The truth is your best defense against neurodegenerative disease. It’s time to demand reforms on many levels to safeguard caregivers, family members and our food and water supplies. Despite all of the warning signs, government and industry are insisting that we waste more time, money and lives studying these issues to death. The infection is real. The body count is real. The denial is disturbing.

Alzheimer’s Disease Research via http://crossbowcommunications.com/is-alzheimers-disease-contagious/

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Crossbow Communications specializes in issue management and public affairs. Alzheimer’s disease, Creutzfeldt-Jakob disease, chronic wasting disease and the prion disease epidemic is an area of special expertise. Please contact Gary Chandler to join our coalition for reform gary@crossbow1.com.

Creutzfeldt-Jakob Disease And Alzheimer’s Disease Related

Creutzfeldt-Jakob Disease More Aggressive Than Alzheimer’s Disease

Neurodegenerative disease is the fastest-growing cause of death in the world. It’s time to expand the conversation immediately.

Dr. Stanley Prusiner, an American neuroscientist from the University of California at San Francisco, earned a Nobel Prize in 1997 for discovering and characterizing deadly prions and prion disease, also known as transmissible spongiform encephalopathy (TSE). The operative word is “transmissible.”

Prions and Alzheimer's disease

President Obama awarded Prusiner the National Medal of Science in 2010 to recognize the importance of his research. Unfortunately, Prusiner’s science is being ignored and we all are facing a public health disaster because of the negligence and reckless disregard for public health.

TSE is a spectrum disease also known as prion disease. The spectrum includes Alzheimer’s disease, Parkinson’s disease and an extremely aggressive version known as Creutzfeldt-Jakob disease. Prusiner claims that all forms of TSE are caused by infectious proteins known as prions (PREE-ons). The prion spectrum varies in severity. It also varies depending on which region of the brain is impacted first. When the presenting symptom is memory loss, the diagnoses flow along the following chart.

prion disease spectrum

Alzheimer’s disease and Creutzfeldt-Jakob disease (CJD) are essentially the same disease at different points on the same spectrum. Misdiagnosis, suppression of diagnoses, misinformation and mismanagement are contributing to the epidemic

“Creutzfeldt-Jakob disease behaves like Alzheimer’s disease on steroids,” said Dr. Jennifer Majersik, an associate professor of neurology at the University of Utah.

According to neuroscientists Dr. Laura Manuelidis, at least 25 percent of Alzheimer’s diagnoses are not Alzheimer’s disease. These misdiagnoses are actually CJD, which is further up the prion spectrum. CJD, without dispute, is extremely infectious to caregivers and loved ones. Millions of cases of deadly CJD are being misdiagnosed as Alzheimer’s disease. Millions of patients and caregivers are being misinformed, misguided and exposed to an aggressive disease. Misdiagnosis and misinformation regarding prion disease is a matter of life and death. The mismanagement doesn’t end here.

“There is now real evidence of the potential transmissibility of Alzheimer’s,” says Thomas Wiesniewski M.D. a prion and Alzheimer’s researcher at New York University School of Medicine.

Creutzfeldt-Jakob disease often is confused with Alzheimer’s disease because they are very similar and both are always fatal. It seems as though CJD is caused by a more aggressive mutation of the deadly prion than Alzheimer’s disease. The only difference that the medical community discusses is the pace of disease progression. CJD is usually very aggressive and can kill within weeks or months of diagnosis.

Prion disease causes memory loss, impaired coordination, and abnormal movements. It’s not known which patients with brain disease become infectious or when, but both CJD and Alzheimer’s patients are being mismanaged. Informed neurologists won’t touch patients with these symptoms because of the risk of transmission. They are making diagnoses from across the room.

Alzheimer's disease diagnosis

Unfortunately, caregivers and family members are not being warned about the infectivity of CJD and Alzheimer’s disease. The bodily fluids, including blood, saliva, mucus, urine and feces transmit the disease. It’s impossible to sterilize items contaminated with the deadly prions. Millions of patients and caregivers are being misinformed, misguided and exposed to an aggressive disease.

Misdiagnosis and misinformation regarding prion disease is a matter of life and death. The mismanagement doesn’t end here. As such, spouses of those with “Alzheimer’s” disease, for example, are 600 percent more likely to contract the infectious disease.

Alzheimer's disease caregivers

On a larger level, entire communities and watersheds are at risk of permanent contamination from just a single victim, not to mention thousands of infectious victims. Alzheimer’s disease and CJD are an environmental nightmare–a real-world version of Pandora’s lunchbox.

Infectious waste has become a major part of the equation. These forms of brain disease are now spreading to wildlife, livestock and back to humans because of sewage mismanagement and something the industry calls biosolids, which is another name for highly infectious sewage sludge.

 

Wastewater treatment plants are collecting points for prions from infected humans. The sewage treatment process can’t stop prions from migrating, mutating and multiplying before being discharged into the environment where they can kill again. Wastewater treatment plants are spreading infectious waste far and wide because they are incapable of stopping prions. As such, all by-products and discharges from wastewater treatment plants are infectious waste, which are contributing to the global epidemic of neurodegenerative disease among humans, wildlife and livestock. Sewage treatment plants can’t detect or stop prions.

The U.S. Environmental Protection Agency (EPA) has confirmed that prions are in sewage and that there has been no way to detect them or stop them. As such, the EPA has never issued guidance on prion management within wastewater treatment plants. Unfortunately, the EPA’s risk assessment on sewage sludge and biosolids were prepared before the world of science knew about prions. The agency continues to cling to it’s antiquated sludge rule crafted back in the dark ages. It does, however, consider prions a “emerging contaminant of concern.” Meanwhile, its outdated risk assessments are promoting a public health disaster.

“Since it’s unlikely that the sewage treatment process can effectively stop prions, adopting measures to prevent the entry of prions into the sewer system is advisable,” said the Toronto Department of Health, November 2004.

biosolids land application sewage sludge

We explore that failure in policy and protocol elsewhere on this website. Suffice it to say now that prion disease is being mismanaged on many levels around the world. As such, we have an epidemic of neurological disorders among people and wildlife around the world now. There is no reason to assume that livestock are immune from the same epidemic.

Prions are unstoppable and the pathogen spreads through the bodily fluids of victims. Studies confirm that people and animals dying of prion disease contaminate the environment around them because infectious prions are in the urine, feces, blood, mucus and saliva of each victim. These infectious bodily fluids are contributing to the rapid spread of Alzheimer’s and other mutations of prion disease.

Prions shed from humans are the most deadly mutation. Prions from human victims demand more respect than radiation. Infected surgical instruments, for example, are impossible to sterilize and hospitals throw them away. Many factors are contributing to the prion epidemic.

Prions are now the X factor and the common thread among most forms of neurodegenerative disease. Industry and government are not accounting for prions or regulating them. They are ignoring these deadly proteins completely, which violates the United States’ Bioterrorism Preparedness and Response Act of 2002. Other nations also are ignoring laws developed to protect food, air and water.

The Government’s Perspective On CJD

Sporadic CJD: the disease appears with no known risk factors. It accounts for about 85 percent of all cases. Despite the smokescreen of misinformation, these cases are actually acquired due to exposure to prion contamination, which is widespread and spreading further every day.

Hereditary CJD: person has a family history or tests positive for the gene mutation associated with CJD. Only about 5 percent to 10 percent of CJD cases in the U.S. are hereditary.

Acquired CJD: disease is transmitted by exposure to brain or nervous system tissue, usually through certain medical procedures. Food and water contamination are now major pathways.

Initially, individuals with CJD experience problems with muscular coordination, impaired memory and judgment and vision, and personality changes. As the illness progresses, memory impairment becomes severe, and individuals develop involuntary muscle jerks and lose their sight. CJD causes more rapid deterioration of an individual’s abilities than Alzheimer’s disease or most other types of dementia.

Currently, there is no single diagnostic test for CJD. A physician usually rules out treatable forms of dementia, such as encephalitis or chronic meningitis. It’s estimated that at least 25 percent of Alzheimer’s disease diagnoses are wrong. In these cases, the underlying disease is actually CJD, which means that millions of people around the world are walking incubators and prion distributors.

A spinal tap, an electroencephalogram (EEG), computerized tomography (CT) and magnetic resonance imaging (MRI) are all forms of testing and evaluations to make the diagnosis of CJD, but the only way to confirm CJD is by brain biopsy or autopsy.

Like Alzheimer’s disease, there is no effective treatment for CJD. Treatment is aimed at easing symptoms and making the individual as comfortable as possible. Medication can help relieve pain if it occurs.

 

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Crossbow Communications specializes in issue management and public affairs. Please contact Gary Chandler to join our coalition for reform gary@crossbow1.com.

Millions Of People Silently Carrying Prion Disease

Mad Cow, CJD, Alzheimer’s and Chronic Wasting Disease All Caused By Prions

Editor’s Note: It’s interesting that Britain and other nations realize that many people and animals are carriers of deadly brain-eating diseases, but claim that these people and animals do not pose a risk worthy of better management. Denying the infective nature of these people and animals is reckless and will continue contributing to the spread of the contagion–prions. There is no way to stop prions, prevent prion disease or cure prion disease.

Prions and Alzheimer's disease

Around one person in 2,000 in Britain carries the protein linked to the human version of mad cow disease, a figure higher than previous estimates, a study said on Tuesday. But how many people will actually develop the crippling and ultimately fatal disease is unknown, its authors say. They also warn Britain to fight the risk of wider contamination through blood transfusions and surgical instruments.

The study, published online by the British Medical Journal (BMJ), is the most exhaustive attempt yet to quantify the risk to Britons from variant Creuzfeldt-Jakob disease, or vCJD. This is a brain-destroying disorder whose suspected cause lies with eating beef contaminated by mad cow disease, a bovine illness that erupted in Britain in the late 1980s and spread to other countries through cattle exports.

Culls to curb mad cow disease — official name bovine spongiform encephalopathy (BSE) — went into higher gear in the 1990s. But experts have been struggling to calculate the risk for people exposed to the rogue prion protein, called abnormal PrP, during the risk years.

Alzheimers epidemic

The problem is that little is known about the incubation time for vCJD, although it is likely to be long, and not everyone who carries the prion may develop the disease itself.

Researchers led by Sebastian Brandner, a professor of neuropathology at University College London, analyzed 32,441 appendixes that were removed at 41 British hospitals, and tested them for PrP. Sixteen samples were positive, a figure that, when extrapolated across the United Kingdom’s population equates to around one in 2,000. This compares with a previous sample study that put the figure at an average of one in 4,000.

The new estimate cannot be directly described as being twice as high as the previous one, for the two tallies overlap in their upper and bottom range of estimates.

“Our study detected the presence of abnormal prions in the population,” Brandner said in an email exchange with AFP. “However, it is not possible to predict how many will ever develop the disease. Should anyone develop a disease, it may present differently from vCJD.”

So far, an official count by British watchdogs gives a relatively tiny number of vCJD cases, just 177 compared to the millions likely to have been exposed to abnormal PrP.

Brandner said the samples were assessed anonymously, which means it was impossible to know how the patients acquired the prion.

“It is likely, however, that most or all would have acquired (it) through BSE-contaminated food,” he said.

Alzheimer's disease infectious disease

The positive samples came from people of all ages and geographical background. The study says the new figures may be an underestimate, given the limitations of the testing technology and uncertainties about when the prion becomes detectable in lymphoid tissue.

And, it suggests, a broad range of Britons may carry the prion, on the basis of a genetic profile of the appendix samples.

Four of the “positives” came back from people with a so-called VV variation on part of the gene that encodes for prion proteins. Only 15 percent of the British population have this.

By contrast, all of the known cases of vCJD have involved people with the so-called MM variation of the gene, which accounts for 43 percent of the population. Eight of the “positives” were MM.

The other four “positives” were MV, meaning a mixture of the two variants on this part of the gene. People with the MV variant account for nearly 45 percent of the British population.

Still unclear is why so few individuals with the “MM” variant have actually fallen with sick with vCJD.

Also unknown is whether individuals with the “V” component may develop the disease after a very long incubation, or whether in fact they may be shielded from it, says the paper.

The study warns the authorities to maintain their guard.

So far, results indicate “the risks of transmission of vCJD by blood transfusion are low,” it says.

However, “it is unclear how many blood recipients have sub-clinical disease and if their life expectancy is shorter than the incubation time.

“It is essential to continue research into tests to detect abnormal PrP in blood.”

Source: http://www.globalpost.com/dispatch/news/afp/131014/mad-cow-disease-one-2000-uk-carry-protein