Neurodegenerative Disease The Fastest-Growing Cause Of Death
Approximately 50 million people around the world already have Alzheimer’s disease and other forms of dementia. It’s the fastest-growing cause of death in the world. Thanks to misdiagnoses and misinformation, we don’t understand the full scope of the tidal wave that’s hitting millions of new victims every year.
Alzheimer’s disease is a member of an aggressive family of neurodegenerative diseases known as Transmissible Spongiform Encephalopathy (TSE). The operative word is “transmissible.” In fact, new research from Duke University indicates that caregivers of those with dementia are six times more likely to contract the disease than people who are not caregivers. That number will prove to be much higher.
The TSE epidemic represents an environmental nightmare that threatens every mammal on Earth. Related diseases are killing wildlife and livestock around the world. Marine mammals also are vulnerable.
TSEs include Alzheimer’s disease, Creutzfeldt-Jakob disease, mad cow disease and chronic wasting disease in deer. Few, if any, mammals are immune. There is no cure and there is no species barrier.
TSEs are caused by a deadly protein called a prion (PREE-on). Prion disease is unstoppable and the pathogen spreads through bodily fluids and cell tissue. Prions linger in the environment, homes, hospitals, nursing homes, dental offices, restaurants and many other places infinitely. They migrate, mutate, multiply and kill with unparalleled efficiency. Thanks to modern sewage disposal practices, prions are building up in our water supplies. They also are contaminating our crops, parks and yards.
Prions defy all attempts at sterilization and inactivation. Victims of the disease can spread the disease even further via bodily fluids and cell tissue. Victims often are contagious long before they appear sick. Their saliva, urine, blood and feces help spread the pathogen further as they struggle to survive.
Dr. Stanley Prusiner earned a Nobel Prize in 1997 for identifying, naming and studying deadly prions. President Obama awarded Prusiner the National Medal of Science in 2010 to recognize the importance of his research. The importance of his research continues to unfold.
In June 2012, Prusiner confirmed that Alzheimer’s, Parkinson’s, Huntington’s and even ALS are prion diseases similar, if not identical, to CJD in people, mad cow disease in livestock and chronic wasting disease in wildlife. The variations in disease progression could be due to genetics in the patients or mutations in the prion, not different diseases entirely. Prion disease is prion disease.
Although there are many factors contributing to the prion disease epidemic, many lethal pathways are being mismanaged around the globe. As such, we are recycling the pathogen that causes Alzheimer’s right back into our food and water. We’re dumping these killer proteins on crops, parks, golf courses, ski areas and school grounds. Rain and irrigation spread them throughout our communities and watersheds. We’re dumping prions into our food and water supplies with foolish sewage management practices.
A new study confirms that people and animals dying of prion disease are contaminating the environment around them with a deadly and unstoppable protein found in their bodily fluids.
Claudio Soto, PhD, professor of neurology and director of the George and Cynthia W. Mitchell Center for Alzheimer’s Disease and Other Brain Related Illnesses at the University of Texas Medical School in Houston, and his colleagues recently found human prions in urine. The study has been published in the August 7 issue of the New England Journal of Medicine.
The good news is that the research offers hope for earlier diagnosis among the millions of people impacted around the world. The discovery can promote earlier intervention and better disease management. It also can help develop screens to protect our blood supplies from donors with prion disease.
The bad news is that prions in urine, mucus, feces and blood underscore the environmental nightmare associated with Alzheimer’s, Creutzfeldt-Jakob (CJD), Parkinson’s, Huntington’s and prion diseases among livestock and wildlife. Although there are many causes for prion disease, many people and animals are contracting it from environmental exposure (food, water and soil) and then contaminating the environment even more with their own bodily fluids. Once victims die, carcasses also contaminate soil and water.
“This is the first time that prions have been detected in human urine,” Dr. Soto told Neurology Today.
Soto failed to reference urine and blood studies performed earlier by Ruth Gabizon in 2001 and Reichl in 2002. These studies also detected prions in bodily fluids. Despite that detail, Soto’s findings can help focus global attention on the exploding prion problem.
Additional research has determined that the prion pathogen spreads through feces, saliva, blood, milk, soil, water and the tissue of infected animals and humans. If a single person with prion disease discharges bodily fluids or feces into a public sewer system, that sewage system is permanently infected and the amount of contamination will multiply and intensify daily. Everything discharged from that sewage system—reclaimed water and biosolids—can spread the contamination even further.
Once a prion reaches the soil, that soil is permanently contaminated and the entire watershed (water) below that point is at risk forever. Dr. Soto also announced recently that at least some plants grown in sewage sludge and other mediums contaminated with infectious prions can uptake those prions and become infectious. If your food and water is generated in such a watershed, you have a higher risk of contracting prion disease with every sip of water or every bite of food produced locally.
With the help of weather, prions can migrate through wind and water. Rain and snow can rinse them into surface water, groundwater, streams, ponds, lakes, and oceans. Wildlife, livestock and humans can ingest prions from soil, water and food. We can’t afford to take the risk of further contaminating entire watersheds – increasing the pathway to humans, livestock, and wildlife downstream.
This transmissible family of disease is unstoppable for many reasons. In addition, once items are exposed to victims of prion disease, they can never be sterilized again.
Because of these factors and others, we have an epidemic of prion disease exploding around the world right now. The epidemic is worse in some regions of the world than others. For example, the death rate for Alzheimer’s is higher in Finland than any other country in the world. Iceland and the United States are runners up. In fact, the death rate for Alzheimer’s is higher in Washington state than any other known region in the world. These vast discrepancies can only be explained by environmental factors, including food, water and air pathways. Sewage disposal that contaminates local food and water supplies is likely part of the problem.
Alzheimer’s and Creutzfeldt-Jakob disease are indistinguishable. They are essentially the same disease. Medical professionals cannot tell the difference and it’s commonly known in the medical industry that the diagnoses are only a guess and that misdiagnoses are common—if there’s even a substantial difference between Alzheimer’s and CJD. It appears that CJD is caused by a more aggressive mutation of prion than Alzheimer’s, but a deadly prion is a deadly prion. There is no reason to believe that some prions behave differently than others in disease transmission and progression.
The urine and sewage connection helps explain why the global epidemic is exploding. More than 50 million people around the world are known to have these neurodegenerative diseases today. Millions more have the disease, but don’t know it, yet. In addition to these people, millions of infected people around the world have used our sewage systems over the past century. Millions more are using them today. It’s impossible to neutralize or stop prions in even the most sterile environments, including hospitals. It’s ludicrous to think that treated sewage water or biosolids are prion-free. Especially since prions from people are much more infectious than those found in other species (prions become more aggressive as they work their way up the food chain).
The U.S. Environmental Protection Agency (EPA) has confirmed that prions are in sewage and that there has been no way to detect them or stop them. As such, the EPA has never issued guidance on prion management within sewage processing plants. This lack of directive allows budget-strapped states and counties to regulate the practices in a variety of ways that best suit local municipalities and industries.
Dr. Soto’s test changes that equation. Now, the EPA can’t plead ignorance to the dangers of prions in biosolids and reclaimed sewage water. Sewage dumped at sea must be reconsidered. Prions should again be classified as a select agent by the U.S. Department of Homeland Security and the Center for Disease Control. Similar measures should be enacted around the world immediately. Failure to act responsibly is suicide.
Unfortunately, testing will confirm that every sewage system in the world has served people with Alzheimer’s disease and CJD. As such, prions have been incubating, multiplying and migrating out of these systems for many years. The problem is intensifying within and beyond these sewage systems every day.
According to the U.S. EPA, “Prions are extremely resistant to inactivation by ultraviolet light, irradiation, boiling, dry heat, formaline, freezing, drying and changes in pH. Methods for inactivating prions in infected tissues or wastes include incineration at very high temperatures and alkaline hydrolysis.” They didn’t mention hydrogen peroxide, which is how some toilet-to-tap programs hope to kill deadly prions.
The EPA National Water Research Compendium 2009-2014 lists prions eight times as an emerging contaminant of concern in sewage sludge (biosolids), water and manure. The EPA issued what it calls the “Sludge Rule,” which basically disclaims any responsibility for its questionable risk assessments regarding biosolids. The EPA reserves the right to adjust these risk assessments, however, as the test of time disproves its pseudo-science.
Prion researcher Dr. Joel Pedersen, from the University of Wisconsin, found that prions become 680 times more infective in certain soils. Pedersen’s research also found that sewage treatment does not inactivate prions.
“Our results suggest that if prions enter municipal wastewater treatment systems, most of the agent would bond to sludge, survive anaerobic digestion, and be present in treated biosolids,” Pedersen said. “Land application of biosolids containing prions represents a route for their unintentional introduction into the environment. Our results emphasize the importance of keeping prions out of municipal wastewater treatment systems. Prions could end up in sewage treatment plants via slaughterhouses, hospitals, dental offices and mortuaries just to name a few of the pathways. The disposal of sludge represents the greatest risk of spreading prion contamination in the environment. Plus, we know that sewage sludge pathogens, pharmaceutical residue and chemical pollutants are taken up by plants and vegetables.”
“Since it’s unlikely that the sewage treatment or pellet production processes can effectively deactivate prions, adopting measures to prevent the entry of prions into the sewer system is advisable,” said the Toronto Department of Health, November 2004.
Meanwhile, we’re spreading tons of biosolids (sewage sludge) on farmland every day to produce our food. Organic food operations, including fruits, vegetables, meat and dairy are not immune to prion exposure. Research confirms that plants uptake prions and prions certainly contaminate leafy matter and the skin of fruits and vegetables upon contact.
We’re dumping biosolids on parks and golf courses and our backyards where we live and play. Coastal cities and ocean vessels dump their sewage right into the ocean, where prions can enter the food chain again, while washing back on our favorite beaches.
We’re dumping millions of tons of contaminated sewage into the oceans, rivers and on cropland around the world every day. We’re spraying reclaimed wastewater on our parks, golf courses and crops. In some cases, people are drinking reclaimed wastewater that has been recycled to their taps. Municipalities, water companies and sewage districts face new liabilities as never seen before.
The new urine study primarily references what is called variant CJD (vCJD is the supposed strain of prion that causes mad cow disease). I argue that a deadly prion is a deadly prion and all prion diseases should be managed assuming that prions are in the urine of all victims. There is no species barrier. There is no cure. There is no reason to assume that prion diseases referred to as Alzheimer’s, CJD, Parkinson’s, Huntington’s and others are different from each other.
Based on this premise, caregivers and family members must arm themselves with facts that can save their lives. Simple acts can expose family and caregivers to the prion contagion. For example, many household items, including utensils and dishes that belong to people who have Alzheimer’s and Huntington’s are likely infected from saliva. It’s unsafe for others to use these items and people should not donate them to charity.
Despite the mass confusion and concern regarding prion disease, protective and sterilization protocols for Alzheimer’s and CJD are not the same and millions of people are being exposed to prion disease because of false securities. CJD is just the tip of a deadly, incurable iceberg and we all should sit up and pay attention right now. We’re recklessly allowing caregivers and stakeholders to expose themselves and others to the problem.
Although there are multiple causes of, and pathways for, prion disease, reckless policies around the world are contributing to the unstoppable epidemic. It’s spreading further every day. Stakeholders must arm themselves with facts that can promote reform because all infected mammals shed infectious prions in their blood, saliva, mucus, urine and feces. Prions also have been found in milk. In essence, the entire body of a victim is contaminated and must be managed accordingly.
With these risks in mind, we need many reforms to safeguard human health and environmental pathways. We are experts on the issue of prion disease, pathway management. We have influenced public opinion and public policy around the world. Please join us in the pursuit of truth and reform.
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