Neurodegenerative disease is the fastest-growing cause of death in the world. It will soon be the leading cause of death. Unfortunately, most of these deaths will be attributed to other causes, which makes the scope of the prion pandemic a mystery. These neurological diseases are always fatal. There is no cure.
Neurodegenerative diseases—including Alzheimer’s disease, Parkinson’s disease, Creutzfeldt-Jakob disease and others—have been surging around the world for the past 30 years. So-called experts have chalked up the surge to an aging population, genetics, too much fat and alcohol intake and not enough exercise. The truth is that there are many factors that can trigger neurodegenerative disease, including head trauma. That’s why chronic traumatic encephalopathy (CTE) has been on the rise.
When we compare the global surge in autism (a neurodevelopmental disease) to the global surge in neurodegenerative disease, it’s apparent that both began in the late 1900s. An alarming practice began dumping neurotoxins, carcinogens and others toxins into our food, water and air. Answers begin with the truth.
Until recently, few have considered the possibility that Alzheimer’s disease is a transmissible disease. Scientists have finally confirmed that Alzheimer’s disease and other forms of neurodegenerative disease are forms of prion disease—clinically known as transmissible spongiform encephalopathy (TSE). The operative word is “transmissible.”
Dr. Stanley Prusiner, an American neuroscientist from the University of California at San Francisco, earned a Nobel Prize in 1997 for discovering and characterizing prions and prion disease. Unfortunately, prions are impossible to stop. Prions can’t be killed, because they aren’t alive. They are merely a deadly form of protein that migrates, mutates and multiplies. As they move up the food chain, they become deadlier. Once they reach the top of the food chain—humans— they are lethal. Once humans pass them on to other people and to other mammals, they kill with unparalleled efficiency. The deadly spiral only intensifies with time.
Prusiner’s most recent study confirms that Alzheimer’s disease is a prion disease, which means that millions of people with Alzheimer’s disease (and millions who died ahead of them) are highly infectious. Alzheimer’s disease is currently defined based on the presence of toxic protein aggregations in the brain known as amyloid plaques and tau tangles, accompanied by cognitive decline and dementia.
But attempts to treat the disease by clearing out these proteins have been unsuccessful. The new evidence that active Aß and tau prions could be driving the disease – published May 1, 2019 in Science Translational Medicine — could lead researchers to explore new therapies that focus on prions directly. Hopefully, it will lead to many reforms to safeguard public health.
“I believe this shows beyond a shadow of a doubt that amyloid beta and tau are both prions, and that Alzheimer’s disease is a double-prion disorder in which these two rogue proteins together destroy the brain,” said Stanley Prusiner, MD, the study’s senior author and director of the UCSF Institute for Neurodegenerative Diseases, part of the UCSF Weill Institute for Neurosciences. “The fact that prion levels also appear linked to patient longevity should change how we think about the way forward for developing treatments for the disease. We need a sea change in Alzheimer’s disease research, and that is what this paper does. This paper might catalyze a major change in AD research.”
Like prion diseases, misfolded alpha-synuclein and tau protein associated with Parkinson’s disease and Alzheimer’s disease, respectively, have been reported in skin tissues of patients with these conditions. Skin could serve as a screen for early diagnosis, but also for monitoring the accumulation of the misfolded proteins in the brain of these neurodegenerative diseases. It also could be another pathway of transmission.
Since Alzheimer’s disease is a confirmed prion disease, millions of people with Alzheimer’s disease (and millions who died ahead of them) are highly infectious. The evidence continues to stack up, while evidence to the contrary does not exist. In fact, one only needs to dissect the scientific names as proof. Prion is an acronym for proteinaceous infectious disease-causing agent that is believed to be the smallest infectious particle. A prion is neither bacterial nor fungal nor viral and contains no genetic material. Furthermore, remember that the “T” in TSE stands for transmissible. They can’t put Pandora back in the box.
For years, neurologists have been guessing when distinguishing between Alzheimer’s disease and Creutzfeldt-Jakob disease (CJD). In reality, both are forms of TSE and both are on the prion spectrum.
As a spectrum disease, TSE varies in severity and symptoms. The diagnosis depends on which region of the brain is impacted. If the hippocampus is under attack, the person will exhibit problems with memory (Alzheimer’s disease). If the cerebral cortex is under attack, the patient will likely exhibit problems with movement and balance (Parkinson’s disease). Prion disease is a more accurate description of these ailments. Transmissible spongiform encephalopathy is a more accurate description of the threat to public health.
Few cases of prion disease are identical in terms of symptoms and pathology because of the thousands of prion mutations circulating today. The number of mutations is increasing exponentially. Each mutation becomes more deadly.
“Alzheimer’s disease (AD) is the most common neurodegenerative disease in humans. It poses a considerable challenge to healthcare systems,” Prusiner said.
Unfortunately, government and industry are leaving this vital detail behind. Risk assessments for various industrial and professional practices have never been updated accordingly. Every mammal on earth is caught in the crossfire of prion contamination due to the misinformation and mismanagement.
Thanks to no meaningful testing, we don’t know how prevalent prion disease is within people or other mammals, but we know that deadly prions are migrating, mutating and multiplying unchecked. Failure to regulate prions in healthcare, food production, water supplies, blood supplies, drugs and beyond is reckless, if not criminal.
Unfortunately, the CDC quietly took prions off the highly regulated list of select agents because the regulation criminalized entire industries and several reckless practices. It also opened the floodgates to prion mismanagement. Victims are creating new pathways every day.
A previous study published in the journal Nature adds to the evidence about the transmissibility of Alzheimer’s disease between people. A second study by the same scientist in early 2016 supports the claim.
The Prion Pandemic
Alzheimer’s disease alone is taking the lives of 50-100 million people around the world now. Millions will die of the disease this year, while millions more will be diagnosed, misdiagnosed and undiagnosed. The epidemic is more severe in some countries than others.
Prions are in the urine, feces, blood, saliva, mucus, skin and cell tissue of all victims–all human byproducts that are washed, dumped, or flushed down sinks and toilets. One can assume that the waste is extra infectious when it comes from funeral homes, nursing homes, hospitals, dental offices, veterinarians, slaughterhouses and some laboratories.
Wastewater treatment plants are collecting points for prions from infected humans. The sewage treatment process can’t stop prions from migrating, mutating and multiplying before being discharged into the environment where they can kill again. Wastewater treatment plants are spreading infectious waste far and wide because they are incapable of stopping prions. As such, all by-products and discharges from wastewater treatment plants are infectious waste, which are contributing to the global epidemic of neurodegenerative disease among humans, wildlife and livestock.
The U.S. Environmental Protection Agency (EPA) has confirmed that prions are in sewage and that there has been no way to detect them or stop them. As such, the EPA has never issued guidance on prion management within wastewater treatment plants. Unfortunately, the EPA’s risk assessment on sewage sludge (biosolids) was prepared before the world of science knew about prions. The agency continues to cling to its antiquated sludge rule crafted back in the dark ages. It does, however, consider prions an “emerging contaminant of concern.” Meanwhile, its outdated risk assessments are promoting a public health disaster.
“Our results suggest that if prions enter municipal wastewater treatment systems, most prions would bond to sewage sludge, survive anaerobic digestion, and be present in treated biosolids,” Pedersen said. “Land application of biosolids containing prions represents a route for their introduction into the environment. I emphasize the importance of keeping prions out of municipal wastewater treatment systems.”
Pedersen also found that sewage treatment does not inactivate prions. Therefore, prions are lethal, mutating, migrating and multiplying everywhere sewage (biosolids) is dumped.
Prions could end up in sewage treatment plants via slaughterhouses, hospitals, dental offices and mortuaries just to name a few of the pathways. The disposal of sludge represents the greatest risk of spreading prion contamination in the environment. Plus, we know that pathogens, pharmaceutical residue and chemical pollutants found in sewage sludge are taken up by plants and vegetables.”
Thanks to the mismanagement of infectious waste, including sewage, the animal world is contracting prion disease from humans. They also are passing it among themselves via their own bodily fluids. When it comes to prion disease, species barriers are a myth.
Prions + Pathways = Victims
To contain prion disease, we must start with the facts. Prion disease is a pathway disease. Failure to acknowledge any pathway and isolate it is negligence. Failure to regulate and contain prions is a violation of the Bioterrorism Preparedness and Response Act of 2002.
Once unleashed on the environment, prions remain infectious. They migrate, mutate and multiply as they infect crops, water supplies, wildlife, livestock, sea mammals and humans. According to prion researcher Joel Pedersen at the University of Wisconsin, prions in soil become up to 680 times more infectious. From there, they migrate, mutate and multiply. It’s a real world version of Pandora’s Lunchbox.
Dumping millions of tons of infectious waste from humans in forests and on farms, parks, golf courses, playgrounds and beyond. Just last November the U.S. EPA backtracked on 40 years of lies when it admitted that it doesn’t fully understand the risks associated with dumping biosolids (infectious/toxic/radioactive waste) on land. As such, the dumping is illegal, yet the practice has not been stopped. Sick deer, elk, moose, reindeer and sea mammals are just canaries in the proverbial coalmine.
The global surge in autism, Alzheimer’s disease, Parkinson’s disease and chronic wasting disease all began at the same time. It’s more than a coincidence. Misinformation is being spread in abundance. Corruption, negligence and incompetence are fanning the flames. Answers begin with the truth. Millions of caregivers and healthcare professionals deserve the truth. Entire communities deserve a chance to defend themselves.
The risk assessments prepared by the U.S. EPA for wastewater treatment and sewage sludge are flawed and current practices of recycling this infectious waste are fueling a public health disaster.
Deliberately poisoning people, livestock and wildlife with infectious waste, radioactive waste, carcinogens, neurotoxins (prions) and other forms of bioterrorism is a sad statement about homeland defense and public health. It’s time to divert all sewage sludge to lined landfills to protect human health, animal health and entire watersheds. Sewage sludge is a prion super-highway. It’s killing more than our wildlife.
Reforms and Recommendations
There is no prevention or cure for Alzheimer’s disease, but smart nutrition and heart health (exercise pumps more blood to the brain) can save your life. Man-made drugs to prevent or treat prion disease have been a total failure.
Gary Chandler is a prion expert. He is the CEO of Crossbow Communications, author of several books and producer of documentaries about health and environmental issues around the world. Chandler is connecting the dots to the global surge in neurodegenerative disease, including Alzheimer’s disease, Parkinson’s disease, Creutzfeldt-Jakob disease, chronic wasting disease and other forms of prion disease. The scientific name for prion disease is transmissible spongiform encephalopathy. The operative word is transmissible.