Neurodegenerative diseases are the fastest-growing causes of death around the world. The mismanagement of infectious waste is contributing to the epidemic.
Dr. Stanley Prusiner earned a Nobel Prize in 1997 for his pioneering research on deadly prions—an infectious form of protein that connects a deadly spectrum disease called transmissible spongiform encephalopathy (TSE). The operative word is “transmissible.”
President Obama awarded Prusiner the National Medal of Science in 2010 to recognize the importance of his work. Unfortunately, this groundbreaking research is being ignored. This negligence is fueling a public health disaster around the world, as critical pathways are being ignored and mismanaged. The mismanagement also is contributing to the global surge in autism.
“Alzheimer’s disease (AD) is the most common neurodegenerative disease in. Aggregation of the β-amyloid (Aβ) peptide within the brain is thought to spark the AD pathogenesis. Many recent studies in transgenic mice have proven that Aβ aggregates become self-propagating (infectious) during disease, leading to a cascade of protein aggregation in the brain, which may underlie the progressive nature of AD. The ability to self-propagate and the existence of distinct “strains” reveals that Aβ aggregates exhibit many properties indistinguishable from deadly prions. We have evidence that Aβ can become a prion during disease,” said Prusiner. “I learned that scrapie, Creutzfeldt-Jakob disease and kuru had all been shown to be transmissible by injecting extracts of diseased brains into the brains of healthy animals. Whether prions are responsible for common neurodegenerative diseases, such as Alzheimer’s disease is a possibility that should not be ignored.”
In June 2012, Prusiner confirmed that Alzheimer’s, Parkinson’s, Huntington’s and even ALS are prion diseases similar, if not identical, to Creutzfeldt-Jakob disease. The primary difference being which part of the brain the disease attacks first. The other variable is that there are now an unknown number of prion mutations. Mutations of these deadly prions are the common denominator between all forms of TSEs. Most of the carnage is being swept under the rug as the problem escalates.
“There is now real evidence of the potential transmissibility of Alzheimer’s,” says Thomas Wiesniewski M.D. a prion and Alzheimer’s researcher at New York University School of Medicine. “In fact, this ability to transmit an abnormal conformation is probably a universal property of amyloid-forming proteins.”
Although there are many causes contributing to prion disease, many people and animals are contracting it from environmental exposure (food, water and soil) and then contaminating the environment even more with their own bodily fluids. Victims of prion disease are walking time bombs. Creutzfeldt-Jakob disease (CJD) is the most deadly form of prion disease in humans. Without dispute, it is a very contagious disease that kills rapidly. There is no cure for CJD, Alzheimer’s and other forms of prion disease.
It appears that CJD is caused by a more aggressive mutation of prion than Alzheimer’s, but a deadly prion is a deadly prion. There is no reason to believe that some prions behave differently than others in disease transmission and progression. There should be no difference in disease management.
Unfortunately, as more people contract these brain diseases, the more deadly wastewater streams become. Meanwhile, wastewater reuse is surging around the world in response to growing populations and dwindling water resources. Other by-products from the wastewater stream known as biosolids (sewage sludge) also are being used to fertilize crops, pastures for livestock, golf courses, playgrounds and gardens. Millions of people, including your family, are in harm’s way because wastewater treatment plants can’t stop prions.
Prion researcher Dr. Joel Pedersen, from the University of Wisconsin, found that prions become 680 times more infectious in certain soils. Pedersen also found that sewage treatment does not inactivate prions. Therefore, prions are lethal, mutating, migrating and multiplying everywhere sewage is dumped.
“Our results suggest that if prions enter municipal wastewater treatment systems, most of the agent would bond to sewage sludge, survive anaerobic digestion, and be present in treated biosolids,” Pedersen said. “Land application of biosolids containing prions represents a route for their unintentional introduction into the environment. Our results emphasize the importance of keeping prions out of municipal wastewater treatment systems.
Prions could end up in sewage treatment plants via slaughterhouses, hospitals, dental offices and mortuaries just to name a few of the pathways. The disposal of sludge represents the greatest risk of spreading prion contamination in the environment. Plus, we know that sewage sludge pathogens, pharmaceutical residue and chemical pollutants are absorbed by plants and vegetables grown in sewage sludge.”
Regulators and industry are playing dumb as the body count keeps rising. It’s a deadly circle enabled by an outdated risk assessment. Modern science is being ignored.
The largest prion pathway in the world is wastewater (infectious waste) from homes, hospitals, nursing homes, slaughterhouses, dental offices and other high-risk sources. The problem is that prions are in all bodily fluids and cell tissue of millions of victims who often go undiagnosed. Their mucus, saliva, feces, and urine are flushed down millions of toilets and rinsed down sinks every day. Once inside the wastewater system, prions proceed to migrate, mutate and multiply. Reckless risk assessments enable wastewater treatment plants to spread these deadly agents far and wide. Deadly prions are building up and incubating in wastewater treatment plants and then dumped openly on land. They are swept into the air by the wind. Now, water contaminated by prions is migrating into our rivers, lakes and oceans. It’s being injected into groundwater and it’s being recycled as tap water.
I used to support wastewater reclamation and reuse projects until I realized that the risk assessments were prepared decades ago—before Dr. Prusiner characterized prions and prion disease. These microscopic protein particles have converted sewage and its by-products a public health disaster.
Gary Chandler is a prion expert. He is the CEO of Crossbow Communications, author of several books and producer of documentaries about health and environmental issues around the world. Chandler is connecting the dots to the global surge in neurodegenerative disease, including Alzheimer’s disease, Parkinson’s disease, Creutzfeldt-Jakob disease, chronic wasting disease and other forms of prion disease. The scientific name for prion disease is transmissible spongiform encephalopathy. The operative word is “transmissible.” Even the global surge in autism appears to be related.