Pomegranate Seeds Treat Neurodegenerative Disease

Alzheimer’s Disease Treatment Delivers Powerful Antioxidant

Granalix BioTechnologies has developed a new treatment for those with Alzheimer’s disease. The company announced the availability of GranaGard™ a food supplement based on pomegranate oil that helps prevent neurodegeneration.

Alzheimer's disease prevention tips

GranaGard, is a submicron Pomegranate Seed Oil (PSO) emulsion, and is an innovative formulation of one of the strongest natural antioxidants, Punicic acid (an Omega 5 lipid), which constitutes 80 percent of PSO. The novel patented formulation was shown to delay disease onset and prevent neuronal death in a model of genetic prion disease (a form of Mad Cow Disease)[i] and to reduce disease burden in a mouse model of Multiple Sclerosis[ii], while showing no toxicity after long term administration. In both diseases, GranaGard administration results in reduction of brain lipid oxidation, which is caused by increased levels of reactive oxygen species (ROS).

Prof. Ruth Gabizon, Founder and acting CEO of Granalix BioTechnologies, explained, “Reactive Oxygen species (ROS) are chemically active molecules that can lead to significant damage to cells, and in particular in the central nervous system. It is therefore widely accepted that this chemical agent contributes to chronic inflammation and neurodegenerative diseases. And while anti-oxidants that can counteract ROS are ubiquitously present in a healthy human diet, their activity is limited by chemical degradation, poor bioavailability, reduced distribution to the CNS, and sub-pharmacological doses.

Alzheimer's disease treatment

To overcome these limitations, we generated GranaGard, a novel neuroprotective formulation with high bioavailability. In addition to its protective role in subjects at risk of neurodegenerative conditions, GranaGard is expected to be effective for general neurological wellbeing for the larger public. We are also currently testing GranaGard for its effect in various non-neurological diseases and as a protective agent during intense exercise.”

PSO submicron droplets have several advantages. First, the nano formulation may avoid the first passage of the oil through the liver, thereby enhancing the availability of the droplets to other organs such as the CNS. GranaGard is then able to enter the brain and protect membrane lipids from ROS attacks that occur as a result of both every-day efforts and pathological events. In vivo, Punicic Acid is metabolized into Conjugated Linoleic Acid (CLA), a compound known for its neuroprotective and other beneficial effects. When mice are given the GranaGard formulation, CLA was found to accumulate in the brain and can directly exert its neuroprotective effect.

Neurodegenerative diseases, such as Alzheimer’s disease, Creutzfeldt-Jacob disease, Parkinson’s or Amyotrophic Lateral Sclerosis (ALS) are late onset brain disorders that together affect millions of people around the globe. Alzheimer’s disease is already the 5th leading cause of death for people aged 65 or older in the US. It’s also the fastest-growing cause of death globally. Currently, there are no preventive or curative treatments for these conditions.

“GranaGard can currently be purchased at the Company’s website. We are seeking additional partners for worldwide distribution,” added Prof. Gabizon. GranaGard™ is produced by Supherb and can be purchased at the Company’s website at http://www.granalix.com.

Granalix BioTechnologies focuses on developing science-based novel formulations of natural antioxidants that can be used for the prevention and treatment of neurodegenerative conditions. The Company was established in 2014 by Prof. Ruth Gabizon from the Department of Neurology at Hadassah Medical Center, Jerusalem, Israel and Prof. Shlomo Magdassi at the Casali Center for Applied Chemistry, the Institute of Chemistry and the Center for Nanoscience and Nanotechnology at the Hebrew University of Jerusalem.

Posted in Alzheimer's Disease, Alzheimer's Disease Prevention, Alzheimer's Disease Treatment, Nutrition | Tagged , , , | Leave a comment

New Drug Offers Promise Against Alzheimer’s Disease

Treatment Purges Plaque Deposits Within Brain

A new drug that can treat Alzheimer’s disease is finally on the horizon after scientists proved they can clear the sticky plaques from the brain which cause dementia and halt mental decline. Hailed as the best news in dementia research for 25 years, the breakthrough is said to be a potential game changer for people with Alzheimer’s disease.

aducanumab treats Alzheimer's disease

Red areas represent plaque deposits targeted by aducanumab. Click to enlarge.

Scientists said they were amazed to find that patients treated with the highest dose of the antibody drug aducanumab experienced an almost complete clearance of the amyloid plaques that prevent brain cells communicating, leading to irreversible memory loss and cognitive decline.

Crucially they also found that after six months of the treatment, patients stopped deteriorating compared with those taking a placebo, suggesting that their dementia had been halted.

If shown to be effective in larger trials, the first drug to treat dementia could be available in just a few years.

“The results of this clinical study make us optimistic that we can potentially make a great step forward in treating Alzheimer’s disease,” said Prof Roger Nitsch, at the Institute for Regenerative Medicine at the University of Zurich. “In the high dose group the amyloid has almost completely disappeared. The effect size of this drug is unprecedented. Despite it being a small sample, there appeared to be a slowing of cognitive decline and functional decline. The group with a high degree of amyloid removal were basically stable. If we could reproduce this, it would be terrific.”

Alzheimer's disease treatment

Dr. Alfred Sandrock, from the Massachusetts-based biotech company Biogen, which is hoping to bring the drug to market, said: “This is the best news that we have had in 25 years and it brings new hope to patients with this disease.”

There are currently 850,000 people living with dementia in Britain, a figure that is expected to rise to one million by 2025 and two million by 2050. There are more than 50 million people battling the disease today. Despite a high death rate, the population of those afflicted with the disease is expected to soar over the next decade.

The most common kind of neurodegenerative disease is Alzheimer’s disease, but scientists have been unable to reach consensus about the cause of the condition, and despite more than 400 drug trials, nothing has been effective. Current treatments can reduce symptoms to some extent but doctors have nothing that can halt or slow progression of the disease.

Aducanumab is a treatment made up of antibodies, tiny y-shaped proteins that latch on to dangerous substances in the body, acting like flags, showing the immune system what to clear away.

Scientists tested various human immune cells with amyloid in a laboratory until they found one which produced an antibody that broke up the plaques. They then cloned it in large numbers for the new therapy, which is given intravenously just once a month.

Prions and Alzheimer's disease

In the trial, which was reported in the journal Nature, scientists tested varying levels of the drug over a year, as well as giving one group a placebo. They found that more amyloid was removed as the dose increased. Brain scans of those given the highest dose shown virtually no amyloid left at all.

The drug is likely to be most effective for patients in the very earliest stages of Alzheimer’s disease, or those who have not yet begun to show symptoms. Several universities are working on early blood tests for dementia which could pick the disease up a decade or more before the first physical signs appear.

Dementia experts and charities said that the breakthrough offered real hope for the future treatment of Alzheimer’s disease. There are now two large phase-three clinical studies taking place to further evaluate safety and efficacy on a total of 2,700 patients with early-stage Alzheimer’s disease and researchers are currently recruiting British participants.

“These results provide tantalizing evidence that a new class of drug to treat the disease may be on the horizon,” said Dr David Reynolds, chief scientific officer at Alzheimer’s Research UK.

“The findings suggest that aducanumab may slow memory and thinking decline in people with early Alzheimer’s and, although the analysis is only exploratory in this early trial, it paints a positive picture for ongoing trials with the drug.”

caregivers Alzheimer's disease

Encouragingly, this treatment also appeared to slow memory decline, demonstrating that amyloid formation is a direct or indirect cause of memory loss. This has been suspected for some time, but has never been proven in humans.

“These findings could be a game changer if the effects on memory decline can be confirmed in more extensive follow-on studies.”

The Alzheimer’s Society said the “most compelling” evidence from the trial was the fact that more amyloid was cleared when patients took higher doses of the drug.

Dr James Pickett, head of research at the charity, said: “No existing treatments for Alzheimer’s directly interfere with the disease process, and so a drug that actually slows the progress of the disease by clearing amyloid would be a significant step.

“While there were hints that it might have an effect on the symptoms of the disease, we need to see the results from further, larger research trials to understand whether this is the case. These larger trials are now under way, including in the UK, and due to finish in 2020.”

Prof Richard Morris, Professor of Neuroscience at the University of Edinburgh, said: “We cannot yet say we have a cure for Alzheimer’s, as this is only a first step … but the importance of this first step cannot be understated.

“Let’s keep our fingers crossed for success in the next steps.”

Alzheimer’s Disease News via http://www.telegraph.co.uk/science/2016/09/01/alzheimers-new-drug-that-halts-mental-decline-is-best-news-for-d/

Posted in Alzheimer's Disease, Alzheimer's Disease Cure, Alzheimer's Disease Treatment, Early Onset Alzheimer's Disease | Tagged , | Leave a comment

Wildlife Contracting Brain Disease From Humans

Chronic Wasting Disease Further Proof Of Infectious Disease

Alzheimer’s disease, Parkinson’s disease and other forms of neurodegenerative disease are collectively becoming the leading cause of death around the world. Brain disease also continues to expand in wildlife. Is there a connection?

biosolids land application contaminates food water

Keep reading to find out why:

  • Alzheimer’s disease is part of a spectrum disease known as prion disease, which also includes Creutzfeldt-Jakob disease. The spectrum also is known as transmissible spongiform encephalopathy (TSE);
  • Alzheimer’s disease is an infectious prion disease, which is often misdiagnosed and undiagnosed. Millions of diagnoses are being suppressed by physicians;
  • The bodily fluids of those with prion disease are infectious;
  • Wastewater treatment plants are contaminating our food and water supplies by spreading deadly prions via sewage sludge, biosolids and reclaimed wastewater. The risk assessments involving these facilities and their by-products were prepared before prions were discovered and characterized;
  • Wildlife, sea mammals, livestock and people are contracting prion disease from mismanaged sewage; 
  • Caregivers are in harm’s way because of disease mismanagement; 
  • It’s time to reclassify sewage sludge, biosolids and reclaimed wastewater as infectious waste; and 
  • It’s time to defend our food, water and air from infectious waste by enforcing the Bioterrorism Preparedness and Response Act Of 2002 and similar laws around the world.

The Brain Disease Epidemic

Alzheimer’s disease alone is killing 50-100 million people now. Millions more will contract the disease this year, while just as many will go undiagnosed and misdiagnosed.

Thanks to misinformation and the mismanagement of infectious waste and bodily fluids, people of all ages are now exposed to an expanding spectrum of brain disease. So are other mammals.

Prions and Alzheimer's disease

The most common forms of neurodegenerative disease include Alzheimer’s disease, Parkinson’s disease, ALS and Creutzfeldt-Jakob disease–the most aggressive and infectious of them all. According to Nobel Prize Laureate Stanley Prusiner, these brain diseases are part of the same disease spectrum—prion disease. It’s also known as transmissible spongiform encephalopathy (TSE). The operative word is transmissible.

Pandora’s Lunchbox

Many factors are contributing to the epidemic. Unfortunately, it appears that Alzheimer’s and Parkinson’s are just as infectious as Creutzfeldt-Jakob disease (CJD). The bodily fluids of people with prion disease are infectious. Prions are the X factor in the global epidemic.

infectious waste and food contamination

Prion disease is a spectrum disease that varies in severity. It also varies depending on which region of the brain is impacted first. It affects most, if not all, mammals. Prion disease causes memory loss, impaired coordination, and abnormal movements. Prions are an infectious form of glycoprotein that can propagate throughout the body. TSE surveillance is important for public health and food safety because TSEs have the potential of crossing from animals to humans, as seen with the spread of mad cow disease. TSEs also have the potential of being transmitted from humans to animals. The most common example is chronic wasting disease (CWD) among deer species. Sick wildlife are a canary in the proverbial coal mine. CWD is part of a larger epidemic of neurological disease that is killing people, wildlife and livestock around the world. The warning signals are being ignored.

land application sewage sludge and chronic wasting disease

CWD was first detected in deer in North America. Then it was detected in a variety of other animals, including an elephant at the Oakland zoo. It’s been found in a variety of animals across the United States and Canada. All hypotheses seem to center around contaminated feed and deer farmers. Then the deer spread the disease via nose-to-nose contact. Those theories were just rocked by the discovery of CWD in Norway in moose and reindeer. The disease didn’t jump the Atlantic from the Americas. However, Norway dumps tons of infectious waste on land every year–infectious waste from people with prion disease.

It’s not known which patients with brain disease become infectious or when. The medical community prefers to ignore the topic. The legal industry is about to have a bonanza because negligence is the rule and not the exception regarding Alzheimer’s disease and the mismanagement of infectious waste. Savvy neurologists won’t touch patients with these symptoms because of the risks. Unfortunately, caregivers aren’t warned accordingly.

Prions are unstoppable. The pathogen spreads through the bodily fluids and cell tissue of its victims. The blood, saliva, mucus, milk, urine and feces of victims are infectious. Wastewater treatment doesn’t touch prions. In fact, these facilities are now helping incubate and distribute prions via solids and wastewater released. Once unleashed on the environment, prions remain infectious. They migrate, mutate and multiply as they infect crops, water supplies and more.

chronic wasting disease

When the U.S. government enacted the Bioterrorism Preparedness and Response Act of 2002, it classified prions as select agents that pose an extreme risk to food, water and much more. Unfortunately, the CDC quietly took prions off the list because the regulation criminalized entire industries and several reckless practices.

Unfortunately, prions linger in the environment, homes, hospitals, nursing homes, dental offices and beyond infinitely. Prions defy all attempts at sterilization and inactivation.

Prions shed from humans are the most deadly. They demand more respect than radiation. They’re being ignored by regulators and industry alike. As such, food and water sources are being contaminated with the deadliest forms of prions. Municipal water systems can’t stop them from reaching water taps in millions of homes. Filtration doesn’t phase them.

Alzheimer's disease research

Scientists have shown that infected tissues can transmit prion disease between animals. There is no species barrier. A new study published in the journal Nature renews concern about the transmissibility of Alzheimer’s disease between people. A second study by the same scientist in early 2016 adds to the stack of evidence. There is no evidence that Alzheimer’s disease is not infectious.

Although there are many causes and pathways contributing to prion disease, many pathways are being mismanaged around the globe. Not only are homes and hospitals exposed to the prion pathogen, so are entire sewage treatment systems. Wastewater treatment plants are prion incubators. Sewage sludge and wastewater pumped out spread the disease.

biosolids land application

The risk assessments prepared by the U.S. EPA for wastewater treatment and sewage sludge are flawed. Many risks are not addressed, including prions and radioactive waste. They don’t mention prions or radiation because there is no answer. Most nations are making the same mistake. Failure to account for known risks is negligent. Crops for humans and livestock grown grown in sewage sludge absorb prions and become infectious. We’re all vulnerable to Alzheimer’s and other forms of prion disease right now due to widespread denial and mismanagement.

Sewage treatment plants can’t detect or stop prions. Just ask the U.S. EPA. If sick deer are serving as a canary in a coal mine, what is this infectious waste doing to livestock and humans?

mad cow disease

It’s time to stop the land application of sewage sludge (LASS) in all nations. Safer alternatives exist. Please join our coalition for reform.

Posted in Alzheimer's Disease, Alzheimer's Disease Causes, Alzheimer's Disease Prevention, Chronic Wasting Disease, Contagion | Tagged , , , | 2 Comments

Caregivers Overwhelmed By Alzheimer’s Disease

eBook Offers Vital Tips For Caregivers, Patients

Neurodegenerative disease is the fastest-growing cause of death in the world. There are no vaccines to prevent it or cure it. Prevention is our best hope and nutrition offers the only proven hope for those who have brain disease.

Alzheimer’s disease is a member of an aggressive family of neurodegenerative diseases known as transmissible spongiform encephalopathy (TSE). As the name implies, the disease is transmissible and extremely difficult to treat.

The good news is that with the truth, caregivers can safeguard themselves and others, while treating patients with targeted nutrition that helps treat the symptoms of Alzheimer’s disease. Targeted nutrition also offers promise in preventing brain disease.

A new book by researcher Gary R. Chandler sheds light on tips for aversion and treatment of Alzheimer’s disease and other forms of neurodegenerative disease. The most common forms of neurodegenerative disease include Alzheimer’s, Parkinson’s and Creutzfeldt-Jakob disease–the most aggressive and infectious of them all.

Prions and Alzheimer's disease

According to Nobel Prize Laureate Stanley Prusiner, they are all part of the same disease spectrum—prion disease. It’s also known as transmissible spongiform encephalopathy (TSE). The operative word is “transmissible.”

TSEs are caused by a deadly protein called a prion (PREE-on). Prion disease is unstoppable. The pathogen spreads through the bodily fluids and cell tissue of its victims. Blood, saliva, mucus, milk, urine and feces carry deadly prions from the victim. All tissue is infectious.

Prions linger in the environment, homes, hospitals, nursing homes, dental offices, restaurants and many other places infinitely. They migrate, mutate, multiply and kill with unparalleled efficiency. Prions defy all attempts at sterilization and inactivation. Victims often become infectious long before they appear sick.

Prions kill everything in their path—man or beast. Prions are highly infectious and the bodies of victims become highly infectious long before they look or feel sick. Blood, milk, meat, urine, saliva, mucus, feces and other bodily fluids of victims are contagious.

According to research from Duke University, caregivers of someone with dementia are six times more likely to develop the condition themselves.

Even sophisticated healthcare systems have failed to grasp the severity of prion disease. Unfortunately, hospitals around the world have been sued for spreading CJD to innocent patients. Most health care systems are still misinformed and under-informed about the dangers that CJD patients pose to others. Therefore, these care facilities are exposing others and contributing to a global mismanagement problem.

Alzheimer's disease infectious disease

Only a decade ago, the idea that Alzheimer’s disease might be transmissible between people would have been laughed away. But scientists have now shown that tissues can transmit symptoms of the disease between animals. A new study published in the journal Nature raises additional concern about the transmissibility of Alzheimer’s disease between people.

Prion disease is a spectrum disease because of its many mutations and because some victims appear to have a genetic predisposition to resist the disease. Some prions can kill people within weeks of exhibiting clinical symptoms, while others can take years. Others may not fall victim to the disease, but can still carry the pathogen internally and externally. Victims become infectious long before they appear sick. Their bodily fluids proceed to contaminate the world around them with infectious waste.

Alzheimer's disease research

Since prion disease is a spectrum disease, doctors can’t tell the difference between Alzheimer’s disease and CJD. It’s a process of elimination and a shot in the dark. The only definitive diagnosis comes with an autopsy, which rarely happens with neurological disease (concerns over deadly contamination). All doctors are guessing with each diagnosis based on the severity of the symptoms. This problem also complicates the search for accurate statistics about the size and scope of the epidemic.

Alzheimer’s diagnoses are wrong at least 20 percent of the time. Unfortunately for caregivers and family members, the protocol for patient care and caregiver safety are vastly different for Alzheimer’s patients and CJD patients. The double standards put many stakeholders at risk. It’s reckless to try to distinguish between prion diseases on the spectrum. In other words, treat people with Alzheimer’s disease as though they have CJD. Assume the worst and hope for the best. A deadly prion is a deadly prion.

infectious waste and food contamination

Although there are many causes and pathways contributing to prion disease, many pathways are being mismanaged around the globe. Not only are homes and hospitals exposed to the prion pathogen, so are entire sewage treatment systems. Wastewater treatment plants are prion incubators. Sewage sludge and wastewater pumped out spread the disease.

Caring For Someone With Alzheimer’s Disease

Nearly 15 million caregivers in the U.S. work with someone who has Alzheimer’s, and approximately 70 percent of Alzheimer’s patients are cared for by relatives and friends. In addition to the truth about transmissibility, these caregivers desperately need guidance on effective treatments. The search for cures has been a total washout.

Fortunately, targeted nutrition offers promise. Some foods increase your risk of contracting brain disease, while some foods help prevent it. Other foods offer the best hope for effective treatment. For example, the eBook explains how walnuts, coconut oil, olive oil, grapes, salmon and hundreds of other foods offer proven results to people with brain disease.

Alzheimer's disease Survival Guide

Order the eBook now and learn how to:

  • Avoid neurotoxins in food, water and the circles of life;
  • Prevent brain disease with targeted nutritional guidance;
  • Effectively treat brain disease with nutritional therapies. It’s the most logical and comprehensive nutritional advice available for neurological disease; and
  • Keep caregivers safe. Misinformation and misdiagnoses are putting us at risk.

treat Alzheimer's disease

Posted in Alzheimer's Disease, Alzheimer's Disease Caregivers, Alzheimer's Disease Prevention, Alzheimer's Disease Treatment | Tagged , , , , | Leave a comment

Alzheimer’s Disease Research Targets Prions

More Evidence That Prions Cause Alzheimer’s Disease

ProMIS Neurosciences highlighted the growing mountain of research, which calls out Amyloid-beta and Tau prions (proteins), as the root cause for Alzheimer’s disease. The company released a white paper today compiling the scientific data as the basis for new treatments.

Prions and Alzheimer's disease

In the white paper, the company provided a concise overview of empirical evidence from a number of leading researchers, much of it recent, that supports the methodology of selectively targeting the prion variants of Amyloid-beta and Tau.

Amyloid-beta (Aβ) acts as a causative agent in the progression of Alzheimer’s disease. Researchers also have discovered that depletion of Aβ reversed cerebral amyloidosis and associated pathology in susceptible mice.

Other research points to the likelihood that prion-like oligomers of misfolded Aβ mediate neurotoxicity and progression of Alzheimer’s disease. In the Cleary et al 2004; Jin et al 2011 studies, scientists concluded that while the presence of Aβ plaque was the calling card of Alzheimer’s disease, the synaptic loss and neurodegenerative spread of the disease were primarily mediated by soluble oligomers of misfolded Aβ rather than plaque.

Alzheimer's disease research

Even more research contends that the progressive nature of Alzheimer’s disease comes from the formation and spread of Aβ prions. As found in the Khan et al 2014 study, the self-propagation of these Aβ prions follows the stereotypical progression of AD. The prion-like spread is well-documented in animal models.

A growing body of data also indicates that the selective targeting of Aβ prions offers distinct advantages over the broadly reactive Aβ antibodies currently in clinical testing. This specificity of Aβ prion neutralization is expected to increase efficacy by mitigating “target distraction.” This means that treating physicians can preserve normal Aβ function in the patient as well as decreasing the risk of edema and vascular adverse effects.

To achieve this precision medicine approach to Alzheimer’s therapy, ProMIS employed two proprietary computational discovery technologies, ProMIS™ and Collective Coordinates to predict regions of protein most likely to unfold based on thermodynamic stability. This means the company was able to identify six predicted disease-specific epitopes of Aβ prions that would act as homing beacons for antibody therapy. Antibodies have been raised from five of the epitopes and are currently undergoing screening and validation for prion-specific binding and functional activity.

Read more at http://www.stockhouse.com/news/newswire/2016/06/23/promis-t-pmn-white-paper-affirms-a%CE%B2-and-tau-prions-as-alzheimer-s-root-cause#u1wxD4DCfkxcIGMw.99

Posted in Alzheimer's Disease, Alzheimer's Disease Causes, Alzheimer's Disease Research, Alzheimer's Disease Treatment, Prion Disease | Tagged , , | Leave a comment

Hallucinogen From Amazon Offers Promise Against Alzheimer’s Disease

Neurogenesis A Possible Treatment For Alzheimer’s Disease

Scientists have discovered that a hallucinogenic substance from the Amazon stimulates the birth of new brains cells and could lead to treatment for neurodegenerative diseases such as Alzheimer’s disease.

The tea called ayahuasca, is also used a as traditional spiritual medicine in ceremonies in Peru. The Saint Pau Hospital Barcelona, which worked in collaboration with the Beckley Foundation and Spanish National Research Council in Madrid, has released the findings from a study investigating the potential of ayahuasca to promote neurogenesis – which is the development of new brain cells. The investigators believe that these findings will open up a new avenue of research that may help develop drugs to treat diseases, such as like Alzheimer’s, Parkinson’s and addiction.

Ayahuasca and Alzheimer's disease

Dr. Jordi Riba, lead investigator, presented preliminary data, at the Interdisciplinary Conference on Psychedelic Research in Amsterdam at the weekend. Results showed two compounds – harmine and tetrahydro harmine – which are found in the hallucinogenic tea, potently stimulated the transformation of stem cells into new neurons.

Amanda Feilding, director of the Beckley Foundation said: “The images from the Beckley/Saint Pau collaboration showing the birth of new neurons are very interesting and suggest that ayahuasca could lead to a new approach in the treatment of neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease.”

Experts have believed for years that the brain doesn’t make neurons during adulthood. In the 1990s, research changed this finding, showing that new neurons are generated throughout adult life in two regions of the human brain: the area around the ventricles and in the hippocampus.

ayahuasca and Alzheimer's disease treatment

The hippocampus, which is thought to be the center of emotion and the autonomic nervous system, plays a key role in memory. Its function declines with age and in neurological disorders. Under normal conditions, the rate of the birth of new neurons is very low, and it cannot keep up with the rate of neural death that occurs in diseases such such as Alzheimer’s disease.

In the study, neural stem cells were isolated from the hippocampus of adult mice. The stem cells were grown in the lab and substances that are present in ayahuasca were added to the cultures and compared with a saline placebo. Scientists have described the results as impressive, with ayahuasca substances stimulating the transformation of stem cells into new neurons.

Dr. Riba has studied ayahuasca for 20 years. Ayahuasca is a potent hallucinogenic brew used by shamans in the Amazon for centuries for medical and spiritual purposes. Obtained from a mixture of jungle plants, its popularity around the world has hugely increased in recent years, as an aid to spiritual exploration, psychotherapy and healing.

Alzheimer’s Disease Treatments Update via http://www.express.co.uk/life-style/health/680497/alzheimer-s-disease-brain-cells-treatment-halluicongenic-tea-Amazon

Posted in Alzheimer's Disease, Alzheimer's Disease Cure, Alzheimer's Disease Research, Alzheimer's Disease Treatment | Tagged , | Leave a comment

Deaths From Neurological Disease Rising Sharply

Neurodegenerative Disease The Fastest-Growing Cause Of Death

By Dr. Russell Blaylock, M.D.

A new study that was recently published in the journal Surgical Neurology International confirms what I wrote about several years ago — that the incidence of neurological disease and the deaths from these disorders has risen dramatically in the last few decades.

Alzheimer's disease treatment

This study, which examined death rates from all neurological disorders from 1989 to 2010, found that there was a dramatic increase that affected both male and female Americans between the ages of 55 and 74. It also tracked those people who were 75 and older.

In the 55-74 age group in America, neurological deaths increased 82 percent among males and 48 percent in females. In the same age group from other countries, the rate increased just two percent and one percent, respectively.

For those over age 75 outside of the U.S., the incidence of neurological deaths for males and females rose 117 and 143 percent, respectively. However, for the same population in the United States, those death rates increased an astounding 368 for men and 663 percent for women.

This dramatic rise in neurological deaths was not a common phenomenon associated with other diseases. Over the same period, death rates with other diseases, such as strokes, heart attacks, and cancer actually dropped.

The authors of the paper concluded that this drastic rise in neurological deaths was due to environmental causes, which include:

  • Increased exposure to industrial and agricultural chemicals;
  • Widespread use of the pesticide Round-up;
  • Elevated exposure to mercury, aluminum, and other toxic metals; and
  • Poor diets featuring high sugar and high intakes of oxidized vegetable oils.

Fortunately, we are finding that a change in diet, avoiding exposure to these toxic chemicals, and using special plant extracts, as well as vitamins and minerals can significantly reduce the risk of death from neurological disorders.

treat Alzheimer's disease
Read more: Neurological Disorders and Mortality

Posted in Alzheimer's Disease, Alzheimer's Disease Research, Alzheimer's Disease Statistics, Prion Disease | Tagged , , | Leave a comment

Researchers Examine Infectious Proteins In Parkinson’s Disease

Protein Aggregation Similar To Alzheimer’s Disease

The nerve cells of some people with amyotrophic lateral sclerosis (ALS) can accumulate clumps of a protein called SOD1. A mutation in the SOD1 gene contributes to contraction of the disease, but it has not been clear if the characteristic clumps of the protein associated with the faulty gene are active drivers or harmless byproducts. A new study suggests that they are drivers.

The new study – by Umeå University in Sweden and published in the Journal of Clinical Investigation – finds that when injected into mice, SOD1 protein aggregates spread rapidly, leading to ALS. The authors note that while researchers have known about SOD1 aggregates in nerve cells in ALS patients for a while, it was not clear what role they played in people carrying the faulty gene.

treat Alzheimer's disease

“We have shown that the SOD1 aggregates start a domino effect that rapidly spreads the disease up through the spinal cord of mice,” said Thomas Brännström, co-author and professor of pathology. “We suspect that this could be the case for humans as well.”

ALS destroys motor neurons – the nerve cells that control muscle movement – in the brain and spinal cord. The disorder progresses to paralysis and death. Most patients only live 2-5 years after diagnosis. There are rare exceptions, including the famous theoretical physicist Stephen Hawking, who was diagnosed with ALS more than 50 years ago.

The team identified two different kinds (called A and B strains) of SOD1 aggregates in mice – both of which spread when injected into the animals’ spinal cords. The protein clumps spread in nerve cells along the whole spinal cord, coincident with progression of an ALS-like disease that resulted in death.

For their study, the team used mice genetically modified to carry the human form of the SOD1 gene. The authors note:

“Mice seeded with A or B aggregates developed premature signs of ALS and became terminally ill after approximately 100 days, which is 200 days earlier than for mice that had not been inoculated or were given a control preparation.”

They also note how at the same time, aggregations of both A and B strains of human SOD1 protein propagated throughout the spinal cord and brainstem. Progression rates, distribution and levels of aggregation at the end stage, plus the disease patterns in the tissue, were different for A and B strains.

The researchers conclude that while the two strains of human SOD1 protein aggregates are different, they appear to “spread disease in a prion-like fashion” throughout the central nervous system, resulting in a “fatal ALS-like disease.”

Prions and Alzheimer's disease

Prions are toxic, misshapen proteins that copy themselves and travel along brain networks, clogging up cells along the way. Prions are associated with most, if not all, neurodegenerative disorders in mammals, including mad cow disease and chronic wasting disease.

Another of the researchers, Stefan Marklund, professor of clinical chemistry, concludes their study strongly suggests SOD1 aggregation plays an important role in the progression of ALS, something he and his colleagues suspected.

Brain Disorder Update via http://www.medicalnewstoday.com/articles/309869.php

Posted in ALS, Alzheimer's Disease, Contagion | Tagged , , | 1 Comment

Sewage Sludge Spread On Land Spreading Brain Disease

Infectious Waste Spreading Brain Disease

Brain disease is attacking record numbers of people around the world. Microcephaly in infants is part of the same scourge. The global epidemic is being fueled by infectious waste that’s contaminating our food, water, air and more. This infectious waste contains deadly and unstoppable neurotoxins, but it’s being spread like fertilizer in virtually every country around the world.

biosolids land application contaminates food water

In 1972, world leaders realized that dumping millions of tons of sewage sludge into the oceans killed entire underwater ecosystems. Some nations stopped the dumping immediately. Others did not.

The U.S., for example, finally passed the Ocean Dumping Ban Act of 1988. It required dumping all municipal sewage sludge and industrial waste on land. That meant dumping it into landfills or dumping it openly on land, including farms, ranches, national forests, city parks, golf courses, playgrounds, sport fields and beyond. The Act went into effect in 1992 and it sparked a public health disaster. The practice is spreading tons of pathogens into the lives of people, livestock, wildlife and beyond every day.

Landfills designed to handle these toxins are expensive. So, the dumpers hired a public relations firm to convince innocent citizens that neurotoxins and carcinogens are fertilizer. The PR firm started calling this toxic waste biosolids. It’s even sold in bags at your local home and garden store as soil for your garden and potting plants. It’s death dirt.

infectious waste

Since then, millions of tons of infectious sewage sludge have been given to farmers as fertilizer and dumped into food and water supplies around the world every year. Those farmers and ranchers are being paid to dump deadly sewage sludge on their land and shut up. Sick livestock are sold or buried as quickly as possible. Those that make it to market are consumed by people and pets, while permanently contaminating everything that they touch.

The landowners are held harmless if the sewage sludge causes damage to people or property downwind, downstream or on the dinner table. Landowners are literally making a killing with government assistance. Unfortunately, the practice of dumping extreme quantities of sewage sludge on land has created an even bigger public health problem. It’s killing people, wildlife, livestock and sea mammals downstream.

biosolids land application

Prions are infectious proteins responsible for a group of diseases known as transmissible spongiform encephalopathy (TSE). The operative word is transmissible.

TSEs have a wide range of confusing names, which helps cloak this global disaster:

  • bovine spongiform encephalopathy (mad cow disease) in cattle;
  • scrapie in sheep;
  • Creutzfeldt-Jakob disease in humans; and
  • chronic wasting disease in deer, elk, moose and reindeer.
  • badgers, mink, cats, elephants, dolphins and many other mammalian species have died from TSE. The concept of a species barrier is a myth. A deadly prion is a deadly prion. They don’t discriminate.

According to Nobel Laureate Stanley Prusiner, Alzheimer’s disease, ALS and Huntington’s disease also are on the TSE spectrum. All are fatal, neurodegenerative brain diseases.

Infectious prions are in the bodily fluids of its victims, including blood, urine, mucus, saliva and feces. As such, these victims send prions to the municipal sewage treatment plant where they remain untouched.

“There is now real evidence of the potential transmissibility of Alzheimer’s,” says Thomas Wiesniewski M.D. a prion and Alzheimer’s researcher at New York University School of Medicine. “In fact, this ability to transmit an abnormal conformation is probably a universal property of amyloid-forming proteins.”

A new study published in the journal Nature renews concern about the transmissibility of Alzheimer’s disease between people. A second study by the same scientist in early 2016 adds to the stack of evidence.

Wastewater effluent and sewage sludge applied to land recycles prions into the environment. Once dumped on open land, prions remain infectious. Irrigation, precipitation and wind carry the prions into groundwater, streams, lakes, oceans and airways, including homes, offices and beyond.

wastewater treatment plant

Reckless wastewater treatment policies and practices are now fueling a global epidemic of neurodegenerative disease among people, wildlife and livestock. In fact, Europe just reported its first case of chronic wasting disease in a reindeer in Norway. There will be many more.

The risk assessments for the land application of sewage sludge (LASS) are based on fraud and outdated information. The risk assessments were developed back in the 1970s and 1980s–before we knew about prions and other killers in modern sewage streams, including many forms of infectious medical waste. These outdated risk assessments make the entire practice illegal today under bioterrorism laws. Common sense makes them immoral and a crime against humanity.

Because of these reckless practices, it’s time to reform many laws, practices and policies. For example, it’s vital to demand testing for mad cow disease in beef cattle and hope like hell that dairy producers aren’t spreading the disease in milk, cheese and meat. Wisconsin, dairy land U.S.A., has an epidemic among wild deer. It has dumped sewage sludge in virtually every county. There is no reason to believe that the cattle are immune from the prion epidemic that’s being fueled by sick soil in Wisconsin, Colorado and beyond.

mad cow disease

There is no reliable test for live animals, yet, which means that animal health is paramount for public health. There also is no testing of crops grown in sewage sludge, despite the science that has proven that crops for humans and livestock absorb the toxins and pathogens that they are grown in–including deadly prions.

Ironically, the United States passed homeland defense laws to protect our food and water supplies from potential terrorists. Many other nations followed suit. When the U.S. government enacted the Bioterrorism Preparedness and Response Act of 2002, it classified prions as select agents that pose an extreme risk to food, water and much more. With reckless policy, the U.S. transferred responsibility for the management of select agents to the Centers for Disease Control (CDC–a private corporation that serves as the Coverup Division). These defenders of public health quietly took prions off the list of select agents because the regulation criminalized entire industries and several reckless practices. They obviously chose to defend the bottom line of corporations and the wastewater treatment industry instead of public health.

Unfortunately, prions linger in the environment, homes, hospitals, nursing homes, dental offices and beyond infinitely. They migrate, mutate, multiply and kill with unparalleled efficiency. Prions defy all attempts at sterilization and inactivation.

Prions shed from humans are the most deadly. They demand more respect than radiation. They’re being ignored by regulators and industry alike. As such, food and water sources are being contaminated with the deadliest forms of prions. Municipal water systems can’t stop them from reaching water taps in millions of homes. Filtration doesn’t phase them.

As stated earlier, the risk assessments for biosolids, sewage sludge and reclaimed wastewater were questionable when they were developed and they are total failures now. Plus, these risk assessments do not account for the possibility of sewage sludge dumped on land going airborne via windstorms and tornadoes. These events now leave a trail of sickness and death in their wake. Airborne sewage is a killer. It dumps the toxins, pathogens and superbugs everywhere.

Valley Fever caused by land application of sewage sludge

Unfortunately, the U.S. exported these bad practices to other nations who proceeded to contaminate their food and water supplies with sewage. If hospitals can’t stop prions, neither can the brain surgeons at wastewater treatment plants.

The legislation banning ocean dumping was very explicit about the need to stop dumping potentially infectious medical waste into the oceans. Ironically, the current policy that promotes LASS ignores the risk of infectious medical waste and many other threats. It also ignores radionuclides, endocrine disruptors, birth control pills, antibiotics, flame-retardants and other toxins and superbugs. This toxic waste belongs in a lined landfill not our watersheds and food supplies. It’s time for immediate reforms.

The same sewage-borne toxins and pathogens are still contaminating our oceans. Now, they’re dumped in further upstream. Entire watersheds are now being infected—including the oceans. The body count among people, livestock and wildlife has been stacking up ever since ocean dumping began phasing out. The nightmare is worse than ever.

caregivers Alzheimer's disease

Biosolids and other forms of sewage mismanagement are now contributing to a global epidemic of neurological disease, including Alzheimer’s disease, Parkinson’s disease, autism, mad cow disease, chronic wasting disease, microcephaly and more. Industry and governments are scrambling to blame the global epidemic on anything but contaminated soil, water, food and air. They are playing dumb in the face of fraud and scientific suppression. Negligence is too kind of a word.

Sewage sludge and reclaimed wastewater also contaminate our food with listeria, e-coli, salmonella and other killers. In fact, scientists are forced to come up with deceptive new names for the growing list of sewage-related ailments, including Zika virus, West Nile virus, epizootic hemorrhagic fever, equine herpes, valley fever and others. Industrial disease. Taxpayer dollars at work.

As mentioned earlier, crops contaminated by sewage sludge can uptake prions and deliver them throughout the plant. Crops then deliver deadly prions to mammals that consume them. In fact, infected plants are spreading prion disease to several species, including humans. When hamsters consumed infected wheat grass, the animals were infected with prion disease. Researchers also found deadly prions in plants that just made surface contact with infected urine and feces.

“These findings demonstrate that plants can efficiently bind infectious prions and act as carriers of infectivity, suggesting a possible role of environmental prion contamination in the horizontal transmission of the disease,” said Claudio Soto, the lead investigator from the University of Texas at Houston.

Killer prions are impossible to stop. Prions are contributing to the death of millions of people now. Victims produce and spread prions daily because they’re in the bodily fluids of all victims. Millions of people with brain disease are contaminating their homes and communities, while exposing caregivers and family members to the contagion. The sewage from these victims is contaminating the local wastewater treatment plant and everything that enters or leaves these facilities, including reclaimed wastewater and sewage sludge. Once dumped on open land, these contagions remain infectious as they migrate, mutate and multiply forever.

Prions and Alzheimer's disease

Prions demand containment and isolation, not distribution and consumption through air, food and water. These toxins demand lined landfills not reckless dumping on our dinner tables. Since prions migrate, mutate and multiply, dilution is not a solution. Prions are a public health nightmare, not to mention the carnage taking place among other mammals.

The world has never done an effective job of managing its sewage. It’s an industry that drives by looking in the rear view mirror. It only swerves when the dead-end road is littered with body bags. After enough people get sick and die, new alternatives emerge. Today is no different.

We now have nearly eight billion people competing for food, water, open spaces and places to dump their sewage. As prion disease spreads and as industrial-scale agriculture becomes more intensive, sewage is becoming deadlier by the day. The stakes have never been higher.

The bodies are stacking up. The contamination grows stronger and spreads further every day. It’s time to stop dumping sewage sludge on land because of the prion risk and many others not accounted for in the antiquated and fraudulent risk assessments. It’s time for citizens to defend our land, water and air. Homelands around the world are under assault and ISIS has nothing to do with it. The terrorists are home-grown traitors. It’s treason.

Today, the land application of sewage sludge is killing mammals and more around the world. Pathogens in sludge are causing brain disease, cancer and death. Let’s take a meaningful stand for food safety. Just say no to sewage sludge in our watersheds and food supplies. Safer alternatives exist.

treat Alzheimer's disease

Take a free preview of our new eBook to learn everything that you need to know about the epidemic and the mismanagement. The rest of the book explains how to defend yourself with aversion and targeted nutrition. Eating organic foods is one way to minimize your exposure to sewage-borne toxins and pathogens. There are no silver bullets.

Please join our global coalition of Homeland Defenders. Join our campaign for truth and reform. Please write to Gary Chandler for more information gary@crossbow1.com

Read More At http://crossbowcommunications.com/land-application-of-sewage-sludge-spreading-brain-disease/

Posted in Alzheimer's Disease Prevention, Chronic Wasting Disease, Food Safety, Infectious Disease, Mad Cow Disease, Prion Disease, Sewage Sludge | Tagged , , , , , | 1 Comment

Microcephaly Adds To Global Surge In Brain Disease

Microcephaly, Zika Virus Fueled By Sewage

Brain disease is consuming record numbers of people around the world right now. Microcephaly in infants is just the latest example.

Microcephaly is a nonspecific term used to describe a small head circumference, and can be caused by maternal exposure to a variety of pathogens and toxins, including HIV, alcohol, radiation, or TORCH pathogens (Toxoplasma gondii, other, rubella virus, cytomegalovirus, and herpes simplex virus). It is therefore important that radiologists know what to look for when it comes to Zika.

The global epidemic is being fueled by infectious waste that’s contaminating food, water, air and more. This infectious waste (from people with infectious brain disease) contains deadly and unstoppable neurotoxins, but it’s being spread like fertilizer in virtually every country around the world (if not just dumped openly). The fight against mosquitoes is part of the battle now, but it will miss the war against the source–infectious waste.

microcephaly and Zika virus

Zika virus is an emerging flavivirus initially described in 1947. The first outbreak of Zika virus occurred in 2007 in the Pacific and the virus has spread in this region since 2013, and in the Americas since 2015. Concomitantly, severe neurological complications in adults, fetuses, and neonates have been described. Zika virus is mainly mosquito borne, but non-vector transmission (maternal–fetal, sexual, and blood transfusion) is possible, with an unknown effect on the burden of the disease. Drinking contaminated water also is a growing source. So are foods infected with this contaminated water.

Unfortunately, mosquitoes are not the only pathway from infectious waste to you. Contaminated food, drinking water and the air that we breathe are just as dangerous.

raw sewage and water contamination

Microcephaly, autism, Alzheimer’s disease, Parkinson’s disease, mad cow disease, chronic wasting disease and other neurodegenerative (brain) diseases are now spread by infectious medical wastes. 

To stop the global epidemic of brain disease, we must stop throwing fuel on the fire. Sewage mismanagement is contaminating food, water and air around the world. It’s spreading infectious waste and infectious diseases. Microcephaly is just the latest symptom of the global problem. Thanks to reckless policies, extreme weather now fans the flames. Tornadoes, floods, droughts and rising tides are pushing tons of sewage further into the lives of everyone. It’s a perfect storm.

biosolids land application contaminates food water

The planet has a record human population competing for limited space and resources. We are producing record volumes of sewage, which includes much more than the obvious. Sewage is now the most toxic, unregulated waste stream in the world. It’s become a deadly cocktail of carcinogens, radionuclides, nerve agents, heavy metals, pharmaceuticals, endocrine disruptors and deadly prions—the deadly pathogen responsible for a spectrum of brain diseases called transmissible spongiform encephalopathy (TSE).

The most common forms of TSE include Alzheimer’s, Parkinson’s, ALS and Creutzfeldt-Jakob disease–the most aggressive and infectious of them all. According to Nobel Prize Laureate Stanley Prusiner, they are all forms of prion disease. TSEs also include mad cow disease, chronic wasting disease and many others. It’s also killing sea mammals as oceans around the world continue filling with tons of sewage every day. There is no species barrier to prion disease or toxic exposure.

Prions and Alzheimer's disease

The global surge in neurodegenerative disease among people, wildlife and livestock has been in motion for about 25 years thanks to the reckless dumping of sewage and the land application of sewage sludge as a fertilizer. The epidemic is reaching critical mass as neurodegenerative disease is now consuming the brains of the unborn–not just the aged.

microcephaly epidemic

Unfortunately, we are disposing of record quantities of sewage openly in the streets and rivers. We’re dumping tons of it on pastures, farms, parks, golf courses, sporting fields, forests and beyond. This infectious waste runs off into our water supplies. It’s picked up by the wind and carried to points unknown. Reckless practices, such as the land application of sewage sludge, have opened Pandora’s box. It’s causing irreversible, deadly contamination around the world.

Unfortunately, public servants are deliberately sweeping sewage-related risks under the rug. The risk assessments for the land application of sewage sludge, for example, are fraudulent. They were deliberately skewed to overlook proven public health risks, including airborne pathways. Bending the rules with bad science allowed for the creation of a multi-billion dollar industry and a toxic by-product called biosolids. It’s still deadly sewage sludge.

So-called regulators are overlooking deadly and unstoppable prions in sewage. As such, most sewage dumping and wastewater reclamation practices are illegal and should be stopped immediately. Safer alternatives exist.

sewage treatment and Zika virus

Thanks to this fraud, infectious sewage is being dumped openly in our watersheds and directly on crops. The prion pathogen in sewage, for example, migrates, mutates and multiplies. Prions shed from humans are the most aggressive and deadly. Prions demand more respect than radiation because they don’t deplete in the environment. Plus, each victim becomes a prion incubator and distributor. Prions should be locked away and contained. Not openly distributed and consumed by an unsuspecting public.

As warm weather approaches in the northern hemisphere, mosquitoes are awakening, breeding, biting and spreading sewage-borne diseases again. Reckless sewage dumping is creating a public health disaster. The dynamics associated with climate change are compounding the problems of sewage management. Mosquitoes have more fuel than ever. So does the wind and our water. It’s time to stop the mismanagement and misinformation. The stakes have never been higher.

infected water and disease

Please join our global coalition of Homeland Defenders. Join our campaign for truth and reform. Please write to Gary Chandler for more information gary@crossbow1.com

Read More At http://crossbowcommunications.com/land-application-of-sewage-sludge-spreading-brain-disease/

Posted in Alzheimer's Disease Causes, Alzheimer's Disease Epidemic, Alzheimer's Disease Prevention, Contagion, Infectious Disease, Prion Disease, Sewage Sludge, Water Contamination | Tagged , , , , | Leave a comment