The Truth About Alzheimer’s Disease

Neurodegenerative disease has been surging around the world for the past 30 years. It’s the fastest-growing cause of death and it will soon be the leading cause of death. Alzheimer’s disease alone is taking the lives of 50-100 million people around the world now. Millions will die of the disease this year, while millions more will be diagnosed, misdiagnosed and undiagnosed. The epidemic is more severe in some countries than others. No one really knows the scope of the epidemic.

A variety of factors can trigger neurodegenerative disease, including genetics, head trauma and neurotoxins. Misinformation and mismanagement are fanning the flames.

prions disease and Alzheimer's disease and Creutzfeldt-Jakob disease

Despite millions of deaths, experts suggest that the prevalence of the disease will quadruple by 2050, if not sooner. Unfortunately, there is a growing stack of evidence that Alzheimer’s disease, Parkinson’s disease and other brain diseases are transmissible. Deadly, self-replicating proteins appear to be one of the common threads. Similar proteins appear to be associated with autism and the childhood cases of Creutzfeldt-Jakob disease.

The epidemic is worse in some regions of the world than others. Finland and Iceland were at the top of the list just a few years ago. Now, countries in the Middle East and Persian Gulf states have soared to the top of the list.

In the United States, for example, deaths from Alzheimer’s disease increased 71 percent from 2000 to 2013. During that time, deaths from heart disease decreased 14 percent.

Contrary to popular thought, many forms of brain disease are infectious, including Alzheimer’s disease.

“There has been a resurgence of this sort of thinking, because there is now real evidence of the potential transmissibility of Alzheimer’s,” says Thomas Wiesniewski M.D. a prion and Alzheimer’s researcher at New York University School of Medicine. 

Dr. Stanley Prusiner, an American neuroscientist from the University of California at San Francisco, earned a Nobel Prize in 1997 for discovering and characterizing prions and prion disease. President Obama awarded Prusiner the National Medal of Science in 2010 to recognize the importance of his research. Important reforms to policies to protect public health, however, have been elusive.

prion disease

Prion disease also is known as transmissible spongiform encephalopathy (TSE). The operative word is “transmissible.” Prusiner claims that all forms of TSE are caused by infectious prions.

“Alzheimer’s disease (AD) is the most common neurodegenerative disease in humans and will pose a considerable challenge to healthcare systems in the coming years,” Prusiner said. Aggregation of the β-amyloid (Aβ) peptide within the brain is thought to be an initiating event in AD pathogenesis. Many recent studies in transgenic mice have provided evidence that Aβ aggregates become self-propagating (infectious) during disease, leading to a cascade of protein aggregation in the brain, which may underlie the progressive nature of AD. The ability to self-propagate and the existence of distinct strains reveals that Aβ aggregates exhibit many properties indistinguishable from those of prions composed of PrPSc proteins. The evidence that Aβ can become a prion during disease, Aβ prions may be important for understanding the pathobiology of AD.”

Like prion diseases, misfolded alpha-synuclein and tau protein associated with Parkinson’s disease and Alzheimer’s disease, respectively, have been reported in skin tissues of patients with these conditions. Skin could serve as a screen for early diagnosis, but also for monitoring the accumulation of the misfolded proteins in the brain of these neurodegenerative diseases. It also could be another pathway of transmission.

Prions cause fatal neurodegenerative disease in humans and other mammals by converting the cellular version of prion protein into a toxic form that erodes the brain and body. Prion disease often is described as a wasting disease that causes a loss of body mass and brain mass.

According to neuroscientist Dr. Laura Manuelidis, at least 25 percent of Alzheimer’s diagnoses are not Alzheimer’s disease. These misdiagnoses are actually Creutzfeldt-Jakob disease (CJD), which is further up the prion spectrum. CJD, without dispute, is extremely infectious to caregivers and loved ones but it has not been declared a reportable disease in the U.S. and many other nations. Even the CJD Foundation is failing to inform stakeholders about the risks and mismanagement. Millions of cases of deadly CJD are being misdiagnosed as Alzheimer’s disease, which compounds the epidemic.

Millions of patients and caregivers are being misinformed, misguided and exposed to an aggressive disease. Misdiagnosis and misinformation regarding prion disease is a matter of life and death.

Prion disease is now striking young people, including teenagers, with much greater frequency. It’s also killing clusters of people in the same communities with greater frequency. The mismanagement doesn’t end here.

biosolids land application and disease

Studies confirm that people and animals dying of prion disease contaminate the environment around them because infectious prions are in the skin, urine, feces, blood, mucus and saliva of each victim. These infectious bodily fluids and tissues are contributing to the rapid spread of Alzheimer’s and other mutations of prion disease.

Caregivers and other stakeholders are caught in the crossfire of misinformation and  mismanagement. At the most basic level, this means that a sneeze, a drinking glass and eating utensils are permanent pathways of disease transmission. Anything that ever comes into contact with the bodily fluids of a victim is impossible to sterilize.

On a larger level, it means that entire communities and watersheds are at risk of permanent contamination from just a single victim, not to mention thousands of infectious victims. Alzheimer’s disease is an environmental nightmare–it’s a real-world version of Pandora’s box.

A study published in the journal Nature adds to the evidence about the transmissibility of Alzheimer’s disease between people. A second study by the same scientist in early 2016 adds to the claim. Meanwhile, there is absolutely no evidence to the contrary. Even wildlife are contracting brain disease from people because of the dumping of infectious waste on farms, ranches and forests.

prevent Alzheimer's disease

  • Women are contracting neurodegenerative disease at twice the rate of men;
  • Spouses of those with Alzheimer’s disease are 600% more likely to contract the disease, which is further evidence that it is a transmissible disease. Caregivers, family members and others are in harm’s way because of disease mismanagement and misinformation;
  • People in Finland, Iceland, Sweden and the United States have the highest prevalence of Alzheimer’s disease. Rates in North Dakota, South Dakota and Washington rival the highest rates in the world. Sewage mismanagement and the mismanagement of other forms of infectious waste are responsible for much of the epidemic in these regions and beyond; and
  • Caregivers are being misinformed about the risks associated with exposure to people with Alzheimer’s disease and Creutzfeldt-Jakob disease. 

prion disease transmission

Surgical instruments infected with prions, for example, are impossible to sterilize and hospitals throw them away. Dentistry is full of mismanagement.

Many factors are contributing to the epidemic. Prions are now the X factor. Industry and government are not accounting for prions or regulating them. They are ignoring the threat completely, which violates the Bioterrorism Preparedness and Response Act of 2002 in the United States. Other nations also are ignoring laws developed to protect food, air, water and citizens.

Alzheimer's disease and CJD

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